Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQB42_RS09595 Genome accession   NZ_LR129841
Coordinates   1818165..1818989 (-) Length   274 a.a.
NCBI ID   WP_001036789.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 947 isolate 947     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1813165..1823989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB42_RS09590 - 1816543..1817874 (-) 1332 WP_000390043.1 hemolysin family protein -
  EQB42_RS09595 endA 1818165..1818989 (-) 825 WP_001036789.1 DNA-entry nuclease EndA Machinery gene
  EQB42_RS09600 - 1819028..1819216 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  EQB42_RS09605 murA 1819209..1820492 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQB42_RS09610 - 1820516..1820746 (-) 231 WP_000250392.1 DUF1146 family protein -
  EQB42_RS09615 sepM 1820804..1821841 (-) 1038 WP_000727278.1 SepM family pheromone-processing serine protease Regulator
  EQB42_RS09620 coaD 1821825..1822313 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  EQB42_RS09625 rsmD 1822303..1822842 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQB42_RS09630 asnA 1822907..1823899 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29966.67 Da        Isoelectric Point: 10.1700

>NTDB_id=1116295 EQB42_RS09595 WP_001036789.1 1818165..1818989(-) (endA) [Streptococcus pneumoniae strain 947 isolate 947]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1116295 EQB42_RS09595 WP_001036789.1 1818165..1818989(-) (endA) [Streptococcus pneumoniae strain 947 isolate 947]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment