Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   EQB42_RS05465 Genome accession   NZ_LR129841
Coordinates   1032288..1033097 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 947 isolate 947     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1027288..1038097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB42_RS05450 mutY 1029010..1030185 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  EQB42_RS05455 micA 1030240..1030944 (+) 705 WP_000722076.1 response regulator YycF Regulator
  EQB42_RS05460 micB 1030937..1032286 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EQB42_RS05465 vicX 1032288..1033097 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  EQB42_RS05470 relB 1033188..1033430 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  EQB42_RS05475 - 1033432..1033686 (+) 255 WP_001812387.1 type II toxin-antitoxin system RelE family toxin -
  EQB42_RS05480 - 1033733..1034385 (+) 653 Protein_1038 potassium channel family protein -
  EQB42_RS05485 - 1034645..1035631 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=1116272 EQB42_RS05465 WP_001289493.1 1032288..1033097(+) (vicX) [Streptococcus pneumoniae strain 947 isolate 947]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1116272 EQB42_RS05465 WP_001289493.1 1032288..1033097(+) (vicX) [Streptococcus pneumoniae strain 947 isolate 947]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment