Detailed information NTG0111613

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: HAS68_RS08285
• Genome accession: NZ_CP002007
• Coordinates: 1657928..1658977 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis 05HAS68
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1652928..1663977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HAS68_RS08265 (HAS68_1519)	nadE	1653756..1654580 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
HAS68_RS08270 (HAS68_1520)	-	1655454..1655981 (-)	528	WP_004194600.1	VanZ family protein	-
HAS68_RS08275 (HAS68_1521)	rlmN	1655978..1657090 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
HAS68_RS08280 (HAS68_1522)	-	1657099..1657740 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
HAS68_RS08285 (HAS68_1523)	sepM	1657928..1658977 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
HAS68_RS08290 (HAS68_1524)	coaD	1658964..1659452 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
HAS68_RS08295 (HAS68_1525)	rsmD	1659442..1659981 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HAS68_RS08300 (HAS68_1526)	-	1660280..1661002 (-)	723	WP_013730502.1	hypothetical protein	-
HAS68_RS08305 (HAS68_1527)	-	1661059..1661445 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
HAS68_RS08310 (HAS68_1528)	-	1661445..1661663 (-)	219	WP_004194736.1	YqgQ family protein	-
HAS68_RS08315 (HAS68_1529)	-	1661963..1662565 (-)	603	WP_004194738.1	response regulator transcription factor	-
HAS68_RS08320 (HAS68_1530)	-	1662562..1663656 (-)	1095	WP_024394990.1	histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=111613 HAS68_RS08285 WP_009910567.1 1657928..1658977(-) (sepM) [Streptococcus suis 05HAS68]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=111613 HAS68_RS08285 WP_009910567.1 1657928..1658977(-) (sepM) [Streptococcus suis 05HAS68]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602