Detailed information NTG0111609

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: JL26_RS04925
• Genome accession: NZ_CP009158
• Coordinates: 970098..972671 (+)
• Length: 857 a.a.
• NCBI ID: WP_010785791.1
• Uniprot ID: B8F3H6
• Organism: Glaesserella parasuis strain SH03
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 965098..977671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JL26_RS04905 (JL26_05095)	znuB	965886..966671 (-)	786	WP_010785787.1	zinc ABC transporter permease subunit ZnuB	-
JL26_RS04910 (JL26_05100)	znuC	966682..967467 (-)	786	WP_021109406.1	zinc ABC transporter ATP-binding protein ZnuC	-
JL26_RS04915 (JL26_05105)	mepM	967607..969100 (+)	1494	WP_010785789.1	murein DD-endopeptidase MepM	-
JL26_RS04920 (JL26_05110)	dsbC	969112..969795 (+)	684	WP_010785790.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
JL26_RS04925 (JL26_05115)	clpC	970098..972671 (+)	2574	WP_010785791.1	ATP-dependent chaperone ClpB	Regulator
JL26_RS04930 (JL26_05120)	-	972789..973451 (+)	663	WP_010785792.1	Bax inhibitor-1 family protein	-
JL26_RS04935 (JL26_05125)	polA	973519..976383 (-)	2865	WP_038514201.1	DNA polymerase I	-
JL26_RS04940 (JL26_05130)	hxpB	976529..977176 (-)	648	WP_038514204.1	hexitol phosphatase HxpB	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95847.15 Da
• Isoelectric Point: 5.1144

>NTDB_id=111609 JL26_RS04925 WP_010785791.1 970098..972671(+) (clpC) [Glaesserella parasuis strain SH03]
MNIDKFTSKFQSAIADAQSLAVGKDNPYIEPAHLMLALLKQNDGSITPLVTSLNVQPNRLSSELDGIISRLPQVQGGNTQ
PSQQLFRLLNQCDKLSQQFGDSFISSELFVLAALEDNGDLGKLLKNLGLTKEKVTAAIQQIRGGESVNNQNAEETRQALQ
KYTIDLTERAKAGKLDPVIGRDEEIRRTVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEEDEASRQRLAKLDEDLTAREREYAELEEVWKAEKSALLGTQHIKTELENA
RIEMDQARRENNFEKMSELQYGKIPALEKQLQEAVKREEEGGENHLLRTKVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEVLHKRVIGQSEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDQDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSHLIQENAENMSYDEMKTIVMNVVGQHFRPEFINRIDETVVFHPLDKENIRAIARIQLERLIKRMAERGYEVTVTDAAV
DHIGEAGFDPLFGARPLKRAIQQELENTLAQQILSGKLLPNSPVTVDYQEGRVVAVQ

Nucleotide

• Length: 2574 bp

>NTDB_id=111609 JL26_RS04925 WP_010785791.1 970098..972671(+) (clpC) [Glaesserella parasuis strain SH03]
ATGAATATTGATAAATTTACCAGCAAGTTTCAATCAGCAATTGCCGATGCACAATCTTTAGCCGTTGGCAAAGATAATCC
CTATATTGAACCGGCCCATTTAATGCTTGCCTTGTTAAAGCAAAATGATGGATCAATCACACCGCTTGTCACCAGTTTAA
ATGTGCAACCTAACCGTTTAAGCAGTGAACTTGATGGCATCATCAGCCGTTTGCCACAGGTGCAAGGGGGCAATACACAG
CCGTCACAACAACTTTTCCGTTTGTTAAATCAATGCGATAAGTTGTCGCAACAGTTTGGCGATAGCTTTATTTCATCAGA
GCTGTTTGTACTTGCGGCACTTGAAGATAACGGTGATTTAGGCAAGTTATTGAAAAACTTAGGTTTAACCAAAGAGAAGG
TGACAGCCGCCATTCAACAAATTCGTGGAGGGGAGAGCGTGAATAATCAAAATGCAGAAGAAACGAGACAAGCGTTACAA
AAATATACCATTGATTTAACTGAACGGGCTAAAGCAGGCAAACTTGATCCTGTGATCGGGCGTGATGAAGAGATCCGCCG
TACGGTGCAAGTATTGCAACGCCGTACTAAAAATAACCCAGTGCTTATCGGTGAACCTGGTGTGGGGAAAACGGCGATTG
TCGAAGGTTTAGCACAACGTATTGTCAATGGCGAAGTGCCTGAGGGTTTGAAGAACAAACGGGTATTGTCGTTGGATATG
GGAGCGTTAATTGCAGGAGCAAAATACCGCGGTGAGTTTGAAGAACGTTTGAAAGCGGTATTAAATGAACTTGCCAAAGA
AGAAGGGCAAGTGATCCTGTTTATTGATGAAATTCATACGATGGTTGGGGCAGGTAAAACCGATGGAGCGATGGACGCTG
GTAACTTGTTGAAACCGTCCCTTGCCCGTGGTGAGTTGCACTGTGTCGGGGCGACAACCTTAGATGAATACCGTCAGTAT
ATTGAAAAAGATGCGGCTCTGGAGCGTCGTTTCCAAAAAGTGTTGGTTGATGAACCAACGGTGGAAGACACCATTGCGAT
TTTGCGTGGTTTGAAAGAACGTTACGAAATTCACCATCACGTTCAAATTACCGACCCTGCGATTGTGGCGGCGGCAACTC
TTTCGCACCGCTATATTTCAGATCGCCAGTTACCCGATAAAGCGATTGATTTAATTGATGAAGCGGCTTCCAGCTTGCGT
ATGGAAATCGACTCTAAACCAGAGCCGTTAGATAAACTTGAACGCCGTATCATTCAGTTGAAATTAGAGCGTCAAGCGTT
ACAGAAAGAAGAAGATGAAGCCAGCCGTCAGCGTCTTGCAAAATTAGACGAGGATCTGACCGCTCGTGAACGTGAATATG
CGGAGCTGGAAGAAGTATGGAAAGCAGAAAAATCCGCTCTATTAGGCACGCAACACATTAAAACCGAGTTGGAAAATGCC
CGAATTGAAATGGATCAGGCTCGCCGTGAGAATAACTTTGAAAAAATGTCAGAGTTGCAATACGGCAAAATTCCGGCCCT
TGAGAAGCAGTTGCAAGAAGCGGTAAAACGTGAAGAAGAGGGCGGTGAAAATCATCTGTTACGCACCAAAGTGACTGATG
AAGAAATTGCCGAAGTGCTGTCTAAAGCTACGGGTATCCCTGTATCCAAAATGATGGAGGGGGAAAAAGAGAAACTATTG
CGAATGGAAGAAGTGCTACACAAACGAGTAATCGGTCAAAGTGAAGCCGTTGATGCGGTAGCAAATGCGATCCGACGTAG
TCGAGCAGGCTTGTCTGATCCAAATCGCCCTATCGGTTCATTCCTATTCTTAGGACCGACAGGCGTAGGGAAAACAGAGC
TTTGCAAAACATTAGCCAACTTCCTATTTGACGATCAAGATGCGATGGTGCGGATCGATATGTCCGAATTTATGGAAAAA
CATAGCGTATCTCGCTTAGTCGGTGCACCACCAGGATATGTCGGCTATGAAGAAGGCGGATATTTGACTGAAGCGGTTCG
CCGTCGTCCATATTCGGTTGTGTTGCTCGATGAAGTAGAAAAAGCACACCCAGATGTATTCAACATTTTATTGCAGGTGC
TTGATGATGGTCGTTTAACTGACGGACAAGGTCGTACGGTGGATTTCCGTAATACGGTCGTCATTATGACATCAAACTTA
GGTTCGCACTTAATTCAAGAGAATGCGGAAAATATGAGTTACGATGAAATGAAAACTATCGTGATGAATGTGGTTGGGCA
ACATTTCCGCCCTGAATTTATCAACCGTATTGATGAAACTGTGGTATTCCACCCATTAGATAAAGAAAATATCCGTGCGA
TTGCAAGAATACAGCTTGAACGTCTAATTAAACGTATGGCGGAGCGTGGCTATGAAGTGACGGTGACCGATGCGGCAGTT
GATCATATCGGCGAAGCAGGCTTTGATCCACTCTTTGGGGCAAGACCGCTTAAACGTGCAATTCAGCAAGAGCTTGAAAA
CACCTTGGCACAGCAAATTCTCTCTGGCAAATTGTTGCCGAATAGTCCTGTGACAGTGGATTATCAAGAAGGAAGGGTTG
TGGCAGTTCAGTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-846)

• ATPase family associated with various cellular activities (AAA) (AAA) (201-332)

• AAA lid domain (AAA_lid_9) (340-442)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (92-143)

3D structure

• AlphaFold DB: B8F3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.029	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.398	100	0.441
clpE	Streptococcus mutans UA159	46.21	80.047	0.37