Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E0E14_RS11370 Genome accession   NZ_LR027877
Coordinates   2168451..2169167 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate BPH3244     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2163451..2174167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E14_RS11340 - 2163670..2164296 (+) 627 WP_000522384.1 nitroreductase family protein -
  E0E14_RS11345 - 2164657..2165442 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  E0E14_RS15710 hld 2166039..2166119 (-) 81 WP_000046022.1 delta-hemolysin -
  E0E14_RS11355 agrB 2166409..2166978 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  E0E14_RS11360 agrD 2166975..2167115 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E0E14_RS11365 agrC 2167140..2168432 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  E0E14_RS11370 agrA 2168451..2169167 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E0E14_RS11375 - 2169239..2169346 (+) 108 WP_001790167.1 hypothetical protein -
  E0E14_RS11380 - 2169534..2170493 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  E0E14_RS11385 - 2170490..2171974 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  E0E14_RS11390 - 2172123..2173073 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1116019 E0E14_RS11370 WP_000688492.1 2168451..2169167(+) (agrA) [Staphylococcus aureus isolate BPH3244]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1116019 E0E14_RS11370 WP_000688492.1 2168451..2169167(+) (agrA) [Staphylococcus aureus isolate BPH3244]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment