Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E0E08_RS14855 Genome accession   NZ_LR027873
Coordinates   2824456..2825121 (-) Length   221 a.a.
NCBI ID   WP_000697878.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BPH2070 isolate BPH2070     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2819456..2830121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E08_RS14835 - 2819909..2820022 (-) 114 WP_014937089.1 hypothetical protein -
  E0E08_RS14840 - 2820698..2822698 (-) 2001 WP_000776744.1 ABC transporter permease -
  E0E08_RS14845 - 2822695..2823450 (-) 756 WP_000923764.1 ABC transporter ATP-binding protein -
  E0E08_RS14850 braS 2823558..2824445 (-) 888 WP_000143418.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E0E08_RS14855 braR 2824456..2825121 (-) 666 WP_000697878.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E0E08_RS14860 - 2825147..2825347 (-) 201 WP_000604727.1 hypothetical protein -
  E0E08_RS14865 - 2825545..2826969 (+) 1425 WP_000953739.1 alkaline phosphatase -
  E0E08_RS15675 - 2827029..2827130 (-) 102 WP_000731972.1 SE2200 family small protein -
  E0E08_RS14875 - 2827252..2827707 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E0E08_RS14880 - 2827952..2828713 (-) 762 WP_000323448.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25335.41 Da        Isoelectric Point: 4.6830

>NTDB_id=1115895 E0E08_RS14855 WP_000697878.1 2824456..2825121(-) (braR) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLCKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1115895 E0E08_RS14855 WP_000697878.1 2824456..2825121(-) (braR) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGTGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.095

100

0.991

Multiple sequence alignment