Detailed information NTG1114676

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SABB155_RS09985
• Genome accession: NZ_LN854556
• Coordinates: 1986210..1987253 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BB155
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1981210..1992253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SABB155_RS09955 (SABB155_18270)	-	1981635..1982890 (-)	1256	Protein_1898	aminopeptidase	-
SABB155_RS09960 (SABB155_18290)	-	1982893..1983093 (-)	201	WP_000180460.1	DUF1128 family protein	-
SABB155_RS09965 (SABB155_18300)	-	1983240..1983704 (+)	465	WP_054189636.1	low molecular weight protein-tyrosine-phosphatase	-
SABB155_RS09970 (SABB155_18310)	-	1983711..1983986 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SABB155_RS09975 (SABB155_18320)	-	1984264..1985481 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
SABB155_RS09980 (SABB155_18330)	vraR	1985591..1986220 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SABB155_RS09985 (SABB155_18340)	vraS	1986210..1987253 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SABB155_RS09990 (SABB155_18350)	liaF	1987250..1987951 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SABB155_RS09995 (SABB155_18360)	-	1987966..1988352 (-)	387	WP_001110179.1	hypothetical protein	-
SABB155_RS10000 (SABB155_18370)	map	1988569..1989327 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SABB155_RS10015 (SABB155_18380)	-	1990087..1991073 (+)	987	WP_054189634.1	FUSC family protein	-
SABB155_RS10020 (SABB155_18390)	-	1991582..1991995 (-)	414	WP_077446671.1	hypothetical protein	-
SABB155_RS10025	-	1992024..1992134 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1114676 SABB155_RS09985 WP_001017131.1 1986210..1987253(-) (vraS) [Staphylococcus aureus strain BB155]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1114676 SABB155_RS09985 WP_001017131.1 1986210..1987253(-) (vraS) [Staphylococcus aureus strain BB155]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTTATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACGGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACAAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTCCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCACTTGGTTTAAAAG
ACAAATCATTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1