Detailed information NTG1114585

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: A66_RS08415
• Genome accession: NZ_LN847353
• Coordinates: 1615784..1616851 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain A66
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1610784..1621851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A66_RS08390 (A66_01687)	treR	1610971..1611681 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
A66_RS08395 (A66_01688)	-	1611714..1612517 (-)	804	WP_050314466.1	ABC transporter ATP-binding protein	-
A66_RS12610	-	1612530..1613407 (-)	878	Protein_1644	ABC transporter permease	-
A66_RS08405 (A66_01691)	-	1613419..1614228 (-)	810	WP_053039745.1	ABC transporter substrate-binding protein	-
A66_RS08410 (A66_01694)	amiF	1614847..1615773 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
A66_RS08415 (A66_01695)	amiE	1615784..1616851 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
A66_RS08420 (A66_01696)	amiD	1616860..1617786 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
A66_RS08425 (A66_01697)	amiC	1617786..1619282 (-)	1497	WP_050965632.1	ABC transporter permease	Regulator
A66_RS08430 (A66_01698)	amiA3	1619349..1621328 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=1114585 A66_RS08415 WP_000159554.1 1615784..1616851(-) (amiE) [Streptococcus pneumoniae strain A66]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=1114585 A66_RS08415 WP_000159554.1 1615784..1616851(-) (amiE) [Streptococcus pneumoniae strain A66]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541