Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   A66_RS04460 Genome accession   NZ_LN847353
Coordinates   856422..858224 (+) Length   600 a.a.
NCBI ID   WP_000244123.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 851422..863224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS04440 (A66_00892) rnr 851717..854071 (+) 2355 WP_053039579.1 ribonuclease R -
  A66_RS04445 (A66_00893) smpB 854034..854501 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  A66_RS04450 (A66_00894) tehB 854517..855377 (+) 861 WP_053039580.1 SAM-dependent methyltransferase TehB -
  A66_RS04455 (A66_00895) coiA 855450..856403 (+) 954 WP_000495896.1 competence protein CoiA Machinery gene
  A66_RS04460 (A66_00896) pepF 856422..858224 (+) 1803 WP_000244123.1 oligoendopeptidase F Regulator
  A66_RS04465 (A66_00897) - 858226..858939 (+) 714 WP_016397920.1 O-methyltransferase -
  A66_RS04470 (A66_00898) prsA 859006..859947 (+) 942 WP_053039581.1 peptidylprolyl isomerase PrsA -
  A66_RS04475 (A66_00899) - 860064..860405 (-) 342 Protein_884 transposase -
  A66_RS11695 - 860819..860914 (+) 96 Protein_885 IS630 family transposase -
  A66_RS04485 (A66_00901) - 861169..861789 (-) 621 WP_000780813.1 histidine phosphatase family protein -
  A66_RS04490 (A66_00902) - 861789..862271 (-) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  A66_RS04495 (A66_00903) - 862271..863113 (-) 843 WP_000954126.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69883.76 Da        Isoelectric Point: 4.5469

>NTDB_id=1114568 A66_RS04460 WP_000244123.1 856422..858224(+) (pepF) [Streptococcus pneumoniae strain A66]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QSYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHTIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1114568 A66_RS04460 WP_000244123.1 856422..858224(+) (pepF) [Streptococcus pneumoniae strain A66]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTGCGGATAACC
TACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATAGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCAAGCCTTTTC
ATTCTATGAGCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGCTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTGGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTAGACGA
TGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTCGCCGTGGTG
CCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACTTTGCAAACCAATGTTAAGGTGCAA
AATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAATCTTGGGGA
TTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTATGATACCAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACT
CAGTCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACACCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAGCCTTGGCTG
AAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGACGCCTTTGCAGTCTTTGAACGCCGTTT
AAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.114

99.333

0.667

Multiple sequence alignment