Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AT694_RS10550 Genome accession   NZ_LN831036
Coordinates   2081562..2082278 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain NCTC13435     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2076562..2087278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT694_RS10520 (ERS445051_01988) - 2076777..2077403 (+) 627 WP_033858005.1 nitroreductase family protein -
  AT694_RS10525 (ERS445051_01989) - 2077764..2078549 (+) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  AT694_RS15300 hld 2079149..2079229 (-) 81 WP_000046022.1 delta-hemolysin -
  AT694_RS10535 (ERS445051_01991) - 2079519..2080082 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  AT694_RS10540 (ERS445051_01992) agrD 2080086..2080226 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  AT694_RS10545 (ERS445051_01993) agrC 2080251..2081543 (+) 1293 WP_000387804.1 quorum-sensing sensor histidine kinase AgrC -
  AT694_RS10550 (ERS445051_01994) agrA 2081562..2082278 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  AT694_RS10555 - 2082350..2082459 (+) 110 Protein_2002 hypothetical protein -
  AT694_RS10560 (ERS445051_01995) - 2082647..2083606 (-) 960 WP_001253314.1 carbohydrate kinase -
  AT694_RS10565 (ERS445051_01996) - 2083603..2085087 (-) 1485 WP_000141429.1 sucrose-6-phosphate hydrolase -
  AT694_RS10570 (ERS445051_01997) - 2085236..2086186 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1114329 AT694_RS10550 WP_000688492.1 2081562..2082278(+) (agrA) [Staphylococcus aureus strain NCTC13435]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1114329 AT694_RS10550 WP_000688492.1 2081562..2082278(+) (agrA) [Staphylococcus aureus strain NCTC13435]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment