Detailed information NTG1114246

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: B6D67_RS08070
• Genome accession: NZ_LN831034
• Coordinates: 1507232..1507957 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC8198
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1502232..1512957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B6D67_RS08035 (ERS445054_01603)	rnpM	1502266..1502562 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
B6D67_RS08040 (ERS445054_01604)	nusA	1502578..1503735 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
B6D67_RS08045 (ERS445054_01605)	rimP	1503910..1504446 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
B6D67_RS08055 (ERS445054_01607)	trmB	1504705..1505340 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
B6D67_RS08060 (ERS445054_01608)	ccrZ	1505340..1506131 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
B6D67_RS08065 (ERS445054_01609)	-	1506195..1507229 (-)	1035	WP_010922583.1	ABC transporter permease	-
B6D67_RS08070 (ERS445054_01610)	pptA	1507232..1507957 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
B6D67_RS08075 (ERS445054_01611)	-	1508029..1508448 (+)	420	WP_002983376.1	HIT family protein	-
B6D67_RS08080 (ERS445054_01612)	-	1508445..1508801 (+)	357	WP_002988657.1	hypothetical protein	-
B6D67_RS08085 (ERS445054_01613)	brpA	1508912..1510186 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
B6D67_RS08090 (ERS445054_01614)	-	1510195..1510719 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
B6D67_RS08095 (ERS445054_01615)	tsaE	1510694..1511155 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
B6D67_RS08100 (ERS445054_01616)	-	1511309..1512769 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1114246 B6D67_RS08070 WP_002983379.1 1507232..1507957(-) (pptA) [Streptococcus pyogenes strain NCTC8198]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1114246 B6D67_RS08070 WP_002983379.1 1507232..1507957(-) (pptA) [Streptococcus pyogenes strain NCTC8198]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714