Detailed information NTG1113987

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LACPI_RS08865
• Genome accession: NZ_LN774769
• Coordinates: 1850739..1853180 (-)
• Length: 813 a.a.
• NCBI ID: WP_047915984.1
• Uniprot ID: A0A0D6DYT8
• Organism: Lactococcus piscium MKFS47
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1845739..1858180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACPI_RS08845 (LACPI_1737)	-	1846381..1847295 (-)	915	WP_047915980.1	magnesium transporter CorA family protein	-
LACPI_RS08850 (LACPI_1738)	-	1847452..1848414 (+)	963	WP_047915981.1	asparaginase	-
LACPI_RS08855 (LACPI_1739)	eno	1848570..1849895 (-)	1326	WP_047915982.1	phosphopyruvate hydratase	-
LACPI_RS08860 (LACPI_1740)	hpf	1850106..1850657 (-)	552	WP_047915983.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
LACPI_RS08865 (LACPI_1741)	clpC	1850739..1853180 (-)	2442	WP_047915984.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LACPI_RS08870 (LACPI_1742)	-	1853257..1853697 (-)	441	WP_047915985.1	CtsR family transcriptional regulator	-
LACPI_RS08875 (LACPI_1743)	greA	1854022..1854504 (-)	483	WP_047915986.1	transcription elongation factor GreA	-
LACPI_RS08880 (LACPI_1744)	mltG	1854624..1856189 (-)	1566	WP_047915987.1	endolytic transglycosylase MltG	-
LACPI_RS08885 (LACPI_1745)	rpoE	1856341..1856895 (-)	555	WP_047915988.1	DNA-directed RNA polymerase subunit delta	-
LACPI_RS08890 (LACPI_1746)	-	1857001..1857513 (-)	513	WP_047915989.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 89549.79 Da
• Isoelectric Point: 7.1738

>NTDB_id=1113987 LACPI_RS08865 WP_047915984.1 1850739..1853180(-) (clpC) [Lactococcus piscium MKFS47]
MTQKQTPILQEILKTARIFAAGNGAEYAETQHVLAGMLSVNDSFSQNILTDHDVTIDMALAEIESQHLPEKTLQVSNIKF
SPKVVRLLSEADAFALQNHLSETGSEHLLYILLTDEDNVAKKLLELNKIKTTEIVKDLVELGNLTVKKVTRKAVTPMGKR
DAASDVSASSLTPTLDSVARDVTDDARQGRIDPMIGRDKEIERVIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVDG
NIPISMQGFRLMSLNIANVVAGTKFRGEFEDRMTAIVDEVSQDANTIVFVDELHTIVGAGGGTDSVTDASNIMKPALARG
EFKLIGATTFNEYQKYIEKDAALERRFAKVTVEEPTADETVAILQGLKATFEGFHQVSFDDDAVKAAVQLSVRYMPSRRL
PDKAIDLLDEAAAAVKIATKNNLLEQRALDKQLVSLEAQLQEAVINKAFKAAKALRASLEKQVKQREKVVSKKHISRVAE
TDVFAVVSNLTGVPVTQMSKSEMKRLVNLEKELHKRVIGQSEAVSAVANAIRRSRSGISDDRRPMGSFMFLGPTGVGKTE
LAKALAQTVFGDESSMIRIDMSEYMEKFNTSRLVGAPPGYVGYEEGGQLTEQVRNKPYAVVLFDEAEKAHPDVFNLLLQI
LDDGFITDGKGRKVDFRNTIIIMTSNLGATALRDEKTVGFGTTNQSANYAAMKSRILEELKKQYRPEFLNRIDESIVFHP
LAEKELSDIVKIMVKPLVDRLANRQITLKLSASAYQLIAKHGFDPEYGARPIRKALEKDLENQLSDKLLLGEIVTGSLVT
VGTRSDKLTIKVK

Nucleotide

• Length: 2442 bp

>NTDB_id=1113987 LACPI_RS08865 WP_047915984.1 1850739..1853180(-) (clpC) [Lactococcus piscium MKFS47]
ATGACACAAAAACAGACACCTATACTTCAAGAAATTTTGAAAACAGCGCGTATTTTTGCAGCTGGAAATGGCGCAGAGTA
CGCGGAAACACAACATGTTTTAGCAGGTATGTTATCTGTCAATGATAGCTTTAGTCAAAATATTTTAACTGATCACGATG
TGACGATTGATATGGCATTGGCTGAAATTGAGAGTCAGCACTTACCTGAAAAAACACTGCAGGTGTCCAATATTAAATTT
TCACCTAAGGTCGTCCGCTTATTATCAGAAGCTGATGCCTTTGCCCTGCAAAATCACTTATCAGAAACAGGCTCTGAACA
CCTGCTTTATATCTTGTTAACAGATGAGGATAATGTCGCTAAGAAACTCCTAGAGTTGAATAAAATCAAGACGACTGAAA
TTGTTAAAGATTTAGTTGAATTGGGTAATCTGACTGTCAAAAAAGTGACTAGAAAAGCAGTCACACCGATGGGGAAACGC
GATGCTGCGTCTGATGTTTCCGCGTCTAGCTTAACACCTACACTTGATTCTGTAGCGCGTGACGTTACAGATGATGCAAG
GCAAGGTCGCATTGACCCTATGATTGGGCGAGATAAAGAGATTGAACGCGTCATCCATATTTTGAGTCGTCGTACAAAAA
ATAATCCTGTCCTCGTTGGTGAGCCAGGTGTTGGTAAATCTGCAATCATTGAAGGACTAGCACAGCGGATCGTAGATGGC
AATATTCCGATTAGCATGCAAGGCTTTCGCTTGATGTCGCTGAACATTGCAAATGTGGTTGCAGGGACTAAATTCCGTGG
GGAATTTGAAGATCGTATGACAGCCATTGTAGACGAAGTCAGTCAAGATGCGAATACGATTGTTTTTGTTGACGAATTAC
ATACGATTGTTGGTGCTGGAGGTGGAACAGATTCGGTAACGGATGCCTCTAATATCATGAAACCAGCACTGGCTCGAGGC
GAGTTTAAACTGATTGGTGCAACAACTTTTAATGAGTATCAAAAGTATATCGAAAAAGATGCAGCCTTAGAACGTCGTTT
TGCAAAGGTAACTGTGGAGGAACCTACAGCAGATGAAACTGTTGCCATTTTACAAGGGTTAAAGGCAACCTTTGAAGGGT
TTCATCAGGTTAGTTTTGATGATGATGCCGTTAAAGCAGCTGTTCAGCTAAGTGTTCGTTACATGCCTAGTCGCAGATTA
CCAGATAAGGCGATTGACTTACTAGATGAGGCAGCAGCTGCTGTCAAAATAGCGACTAAAAATAATTTGCTTGAACAGCG
TGCACTTGACAAGCAACTTGTGTCTTTAGAAGCACAACTCCAAGAAGCAGTCATAAATAAAGCGTTTAAAGCAGCAAAAG
CCTTGAGAGCCTCACTTGAAAAACAGGTGAAGCAACGTGAAAAGGTAGTCAGTAAAAAGCATATCAGTCGTGTAGCAGAA
ACAGATGTATTTGCTGTCGTTTCTAATTTAACTGGTGTGCCAGTCACACAAATGAGCAAAAGCGAGATGAAACGCCTAGT
TAATTTGGAAAAAGAGTTACACAAGCGTGTTATTGGGCAAAGTGAAGCAGTTAGCGCAGTAGCAAATGCAATTCGCAGAA
GCCGTTCGGGTATCTCTGATGATAGACGACCGATGGGGTCGTTCATGTTTTTAGGGCCAACAGGCGTTGGTAAAACAGAA
CTTGCCAAGGCGTTGGCACAAACTGTATTTGGCGATGAGTCTAGTATGATCCGGATTGACATGAGCGAATACATGGAGAA
ATTTAATACGAGCCGATTAGTCGGTGCGCCTCCAGGTTACGTAGGCTATGAAGAAGGCGGACAACTGACAGAACAAGTTC
GCAATAAACCTTATGCGGTCGTCCTTTTTGATGAAGCAGAAAAAGCACATCCAGATGTCTTTAACTTACTCTTACAAATT
CTTGACGATGGGTTTATCACAGATGGTAAAGGTCGCAAAGTTGATTTTCGCAATACAATCATTATTATGACCAGCAATTT
GGGTGCGACAGCCCTACGTGATGAAAAGACAGTCGGCTTTGGTACGACGAATCAATCAGCTAATTATGCGGCCATGAAAT
CTAGAATACTTGAAGAGCTGAAAAAACAATATCGTCCTGAATTTTTAAATCGGATAGATGAAAGTATTGTCTTTCATCCC
TTGGCTGAAAAAGAATTATCTGATATCGTCAAGATTATGGTAAAACCTTTAGTTGATAGATTAGCCAATAGACAGATCAC
TTTGAAGTTATCAGCAAGTGCTTACCAATTAATTGCTAAACATGGCTTTGATCCAGAATATGGTGCAAGACCAATTAGAA
AAGCTTTAGAAAAAGATCTTGAGAATCAACTTTCAGATAAGTTATTGCTAGGCGAGATTGTAACAGGAAGCCTTGTAACA
GTGGGGACTAGAAGTGATAAGCTAACGATTAAGGTAAAATGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-134)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-65)

• AAA lid domain (AAA_lid_9) (357-456)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (217-335)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

3D structure

• AlphaFold DB: A0A0D6DYT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	60.988	99.631	0.608
clpC	Streptococcus thermophilus LMD-9	49.517	100	0.504
clpC	Streptococcus thermophilus LMG 18311	49.275	100	0.502
clpC	Streptococcus pneumoniae Rx1	49.392	100	0.499
clpC	Streptococcus pneumoniae D39	49.392	100	0.499
clpC	Streptococcus pneumoniae TIGR4	49.27	100	0.498
clpC	Streptococcus mutans UA159	47.899	100	0.491
clpC	Bacillus subtilis subsp. subtilis str. 168	47.414	99.877	0.474
clpE	Streptococcus mutans UA159	46.625	78.352	0.365