Detailed information NTG1113702

Bioinformatically predicted

Overview

• Name: agrA
• Type: Regulator
• Locus tag: SRS_RS10585
• Genome accession: NZ_LN626917
• Coordinates: 2074619..2075335 (+)
• Length: 238 a.a.
• NCBI ID: WP_000688492.1
• Uniprot ID: A0A7U7IEW1
• Organism: Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2069619..2080335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SRS_RS10560	-	2070819..2071604 (+)	786	WP_000867948.1	carbon-nitrogen family hydrolase	-
SRS_RS15935	hld	2072206..2072286 (-)	81	WP_000046022.1	delta-hemolysin	-
SRS_RS10570	-	2072576..2073139 (+)	564	WP_001105709.1	accessory gene regulator AgrB	-
SRS_RS10575	agrD	2073143..2073283 (+)	141	WP_000735197.1	cyclic lactone autoinducer peptide AgrD	-
SRS_RS10580	agrC	2073308..2074600 (+)	1293	WP_000387809.1	quorum-sensing sensor histidine kinase AgrC	-
SRS_RS10585	agrA	2074619..2075335 (+)	717	WP_000688492.1	quorum-sensing response regulator AgrA	Regulator
SRS_RS10590	-	2075709..2076668 (-)	960	WP_001253292.1	carbohydrate kinase family protein	-
SRS_RS10595	-	2076665..2078149 (-)	1485	WP_045179730.1	sucrose-6-phosphate hydrolase	-
SRS_RS10600	-	2078298..2079248 (-)	951	WP_000790325.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 238 a.a.
• Molecular weight: 27905.90 Da
• Isoelectric Point: 6.0927

>NTDB_id=1113702 SRS_RS10585 WP_000688492.1 2074619..2075335(+) (agrA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide

• Length: 717 bp

>NTDB_id=1113702 SRS_RS10585 WP_000688492.1 2074619..2075335(+) (agrA) [Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (151-237)

3D structure

• AlphaFold DB: A0A7U7IEW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
agrA	Staphylococcus aureus N315	100	100	1