Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   GBSCOH1_RS08695 Genome accession   NZ_HG939456
Coordinates   1741925..1744372 (-) Length   815 a.a.
NCBI ID   WP_000020286.1    Uniprot ID   -
Organism   Streptococcus agalactiae COH1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1736925..1749372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBSCOH1_RS08670 (GBSCOH1_1670) - 1737206..1738462 (+) 1257 WP_001285395.1 toxic anion resistance protein -
  GBSCOH1_RS08675 (GBSCOH1_1671) hslO 1738602..1739477 (+) 876 WP_000357828.1 Hsp33 family molecular chaperone HslO -
  GBSCOH1_RS08680 (GBSCOH1_1672) dusB 1739461..1740438 (+) 978 WP_000192729.1 tRNA dihydrouridine synthase DusB -
  GBSCOH1_RS08685 (GBSCOH1_1673) - 1740559..1741200 (+) 642 WP_000909520.1 deoxynucleoside kinase -
  GBSCOH1_RS08690 (GBSCOH1_1674) - 1741214..1741705 (+) 492 WP_000586900.1 GNAT family N-acetyltransferase -
  GBSCOH1_RS08695 (GBSCOH1_1675) clpC 1741925..1744372 (-) 2448 WP_000020286.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GBSCOH1_RS08700 (GBSCOH1_1676) - 1744369..1744833 (-) 465 WP_000985641.1 CtsR family transcriptional regulator -
  GBSCOH1_RS08705 (GBSCOH1_1677) - 1745006..1745467 (+) 462 WP_001106578.1 COG2426 family protein -
  GBSCOH1_RS08710 (GBSCOH1_1678) tsf 1745626..1746666 (-) 1041 WP_000808080.1 translation elongation factor Ts -
  GBSCOH1_RS08715 (GBSCOH1_1679) rpsB 1746760..1747530 (-) 771 WP_000268454.1 30S ribosomal protein S2 -
  GBSCOH1_RS08720 (GBSCOH1_1680) ahpC 1747807..1748367 (+) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90627.16 Da        Isoelectric Point: 6.0379

>NTDB_id=1112239 GBSCOH1_RS08695 WP_000020286.1 1741925..1744372(-) (clpC) [Streptococcus agalactiae COH1]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTIGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKHKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=1112239 GBSCOH1_RS08695 WP_000020286.1 1741925..1744372(-) (clpC) [Streptococcus agalactiae COH1]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
AAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTATTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACCATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCATCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGATAAAAAGCATAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

AAA lid domain (AAA_lid_9)

(375-471)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.601

99.632

0.763
  clpC Streptococcus thermophilus LMG 18311

72.761

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.638

100

0.726
  clpC Streptococcus pneumoniae Rx1

68.55

99.877

0.685
  clpC Streptococcus pneumoniae D39

68.55

99.877

0.685
  clpC Streptococcus pneumoniae TIGR4

68.55

99.877

0.685
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.434

100

0.493
  clpC Bacillus subtilis subsp. subtilis str. 168

45.683

100

0.467
  clpE Streptococcus mutans UA159

46.238

78.282

0.362

Multiple sequence alignment