Detailed information NTG1112213

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GBSCOH1_RS02625
• Genome accession: NZ_HG939456
• Coordinates: 471748..472821 (+)
• Length: 357 a.a.
• NCBI ID: WP_000790649.1
• Uniprot ID: A0AB38VS22
• Organism: Streptococcus agalactiae COH1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 466748..477821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBSCOH1_RS02595 (GBSCOH1_0433)	-	467639..468703 (+)	1065	WP_000021310.1	MmcQ/YjbR family DNA-binding protein	-
GBSCOH1_RS02600 (GBSCOH1_0434)	asnA	468818..469810 (+)	993	WP_000748010.1	aspartate--ammonia ligase	-
GBSCOH1_RS02605 (GBSCOH1_0435)	-	469855..470304 (-)	450	WP_000592264.1	bacteriocin transport accessory protein	-
GBSCOH1_RS02610 (GBSCOH1_0436)	rsmD	470435..470974 (+)	540	WP_001873924.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GBSCOH1_RS02615 (GBSCOH1_0437)	-	470986..471276 (+)	291	WP_000384889.1	hypothetical protein	-
GBSCOH1_RS02620 (GBSCOH1_0438)	coaD	471273..471758 (+)	486	WP_000161888.1	pantetheine-phosphate adenylyltransferase	-
GBSCOH1_RS02625 (GBSCOH1_0439)	sepM	471748..472821 (+)	1074	WP_000790649.1	SepM family pheromone-processing serine protease	Regulator
GBSCOH1_RS02630 (GBSCOH1_0440)	-	472896..474230 (+)	1335	WP_000137524.1	bifunctional metallophosphatase/5'-nucleotidase	-
GBSCOH1_RS02635 (GBSCOH1_0441)	-	474299..474877 (+)	579	WP_001224500.1	YutD family protein	-
GBSCOH1_RS02640 (GBSCOH1_0442)	rlmN	474928..476034 (+)	1107	WP_001124996.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
GBSCOH1_RS02645 (GBSCOH1_0443)	-	476034..476549 (+)	516	WP_000919737.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39145.34 Da
• Isoelectric Point: 10.4286

>NTDB_id=1112213 GBSCOH1_RS02625 WP_000790649.1 471748..472821(+) (sepM) [Streptococcus agalactiae COH1]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1112213 GBSCOH1_RS02625 WP_000790649.1 471748..472821(+) (sepM) [Streptococcus agalactiae COH1]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTGCTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGGCTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTAGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGCACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658