Detailed information NTG1112051

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SEB_RS10755
• Genome accession: NZ_HG813242
• Coordinates: 2250931..2251596 (-)
• Length: 221 a.a.
• NCBI ID: WP_001830679.1
• Uniprot ID: A0A2G7HYS8
• Organism: Staphylococcus epidermidis PM221
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2245931..2256596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SEB_RS10735 (SEB_02193)	-	2246461..2247051 (-)	591	WP_001830621.1	DUF4064 domain-containing protein	-
SEB_RS10740 (SEB_02194)	-	2247155..2249167 (-)	2013	WP_001830646.1	ABC transporter permease	-
SEB_RS10745 (SEB_02195)	-	2249169..2249918 (-)	750	WP_001830627.1	ABC transporter ATP-binding protein	-
SEB_RS10750 (SEB_02196)	braS	2250029..2250925 (-)	897	WP_002437988.1	sensor histidine kinase	Regulator
SEB_RS10755 (SEB_02197)	braR	2250931..2251596 (-)	666	WP_001830679.1	response regulator transcription factor	Regulator
SEB_RS10760 (SEB_02198)	-	2251627..2251806 (-)	180	WP_001830653.1	hypothetical protein	-
SEB_RS10765 (SEB_02199)	-	2252104..2253573 (+)	1470	WP_002437984.1	alkaline phosphatase	-
SEB_RS10770 (SEB_02200)	-	2253696..2255240 (-)	1545	WP_010959313.1	NAD(P)H-binding protein	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25629.71 Da
• Isoelectric Point: 5.0250

>NTDB_id=1112051 SEB_RS10755 WP_001830679.1 2250931..2251596(-) (braR) [Staphylococcus epidermidis PM221]
MKIFIVEDDLVIAESLANELSKWNYEVHVVDNFEKIMEDFRRVEPQLVLLDINLPTLNGFHWCQEMRKVSHVPIMFISSR
TDNMDQILAIQMGGDDFIEKPFNLSLTVAKIQALLRRTYDLSIARDEIAVKGCKLIVDEAKLSKDNEHVQLSLTELQILK
LLFQNENKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLLSIGVDDLIETKKNVGYRV

Nucleotide

• Length: 666 bp

>NTDB_id=1112051 SEB_RS10755 WP_001830679.1 2250931..2251596(-) (braR) [Staphylococcus epidermidis PM221]
ATGAAAATTTTCATTGTAGAAGACGATTTAGTGATTGCTGAAAGTTTAGCTAATGAGCTATCTAAATGGAATTATGAGGT
GCATGTGGTTGATAATTTTGAAAAGATAATGGAAGATTTTCGCCGAGTAGAACCACAACTCGTATTATTAGATATCAATC
TACCAACACTTAATGGCTTCCATTGGTGCCAAGAAATGCGAAAAGTATCTCATGTGCCTATTATGTTTATTAGTTCAAGA
ACAGATAATATGGATCAAATTCTGGCTATCCAAATGGGTGGCGATGATTTTATCGAGAAACCATTTAACTTGTCTTTAAC
AGTAGCTAAAATTCAGGCACTATTGCGTCGCACTTATGATTTATCAATAGCTCGTGATGAAATAGCTGTTAAAGGTTGTA
AACTAATTGTTGATGAGGCCAAGCTTAGCAAGGATAATGAACATGTTCAACTTTCCTTAACAGAGCTACAGATATTAAAA
TTGTTATTTCAAAATGAAAATAAATATGTAAGTCGTACAGCTTTAATTGAGAAGTGTTGGGAGTCTGAGAATTTTATTGA
TGACAATACGCTCGCAGTAAATATGACACGATTACGAAAAAAATTACTTTCTATCGGTGTCGATGATTTAATTGAGACAA
AGAAAAATGTAGGATATAGGGTTTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-111)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

3D structure

• AlphaFold DB: A0A2G7HYS8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	79.186	100	0.792