Detailed information NTG1111880

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: SPYH293_RS06400
• Genome accession: NZ_HG316453
• Coordinates: 1311941..1312666 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain H293
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1306941..1317666

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYH293_RS06365 (SPYH293_01300)	rnpM	1306975..1307271 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
SPYH293_RS06370 (SPYH293_01301)	nusA	1307287..1308444 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
SPYH293_RS06375 (SPYH293_01302)	rimP	1308619..1309155 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
SPYH293_RS06385 (SPYH293_01304)	trmB	1309414..1310049 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
SPYH293_RS06390 (SPYH293_01305)	ccrZ	1310049..1310840 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
SPYH293_RS06395 (SPYH293_01306)	-	1310904..1311938 (-)	1035	WP_031577431.1	ABC transporter permease	-
SPYH293_RS06400 (SPYH293_01307)	pptA	1311941..1312666 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
SPYH293_RS06405 (SPYH293_01308)	-	1312738..1313157 (+)	420	WP_002983376.1	HIT family protein	-
SPYH293_RS06410 (SPYH293_01309)	-	1313154..1313510 (+)	357	WP_031488470.1	hypothetical protein	-
SPYH293_RS06415 (SPYH293_01310)	brpA	1313621..1314904 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
SPYH293_RS06420 (SPYH293_01311)	-	1314913..1315437 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
SPYH293_RS06425 (SPYH293_01312)	tsaE	1315412..1315873 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
SPYH293_RS06430 (SPYH293_01313)	-	1316027..1317487 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1111880 SPYH293_RS06400 WP_002983379.1 1311941..1312666(-) (pptA) [Streptococcus pyogenes strain H293]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1111880 SPYH293_RS06400 WP_002983379.1 1311941..1312666(-) (pptA) [Streptococcus pyogenes strain H293]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714