Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACN076_RS08155 Genome accession   NZ_CP184836
Coordinates   1637789..1640047 (+) Length   752 a.a.
NCBI ID   WP_420789809.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1632789..1645047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS08125 (ACN076_08125) - 1632882..1633736 (-) 855 WP_265528451.1 NAD(P)H-hydrate dehydratase -
  ACN076_RS08130 (ACN076_08130) - 1633751..1634572 (-) 822 WP_420789807.1 phosphate ABC transporter ATPase -
  ACN076_RS08135 (ACN076_08135) - 1634709..1635566 (-) 858 WP_000192089.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  ACN076_RS08140 (ACN076_08140) - 1635720..1636454 (-) 735 WP_420789808.1 amino acid ABC transporter ATP-binding protein -
  ACN076_RS08145 (ACN076_08145) - 1636454..1637137 (-) 684 WP_001011641.1 amino acid ABC transporter permease -
  ACN076_RS08150 (ACN076_08150) - 1637328..1637558 (+) 231 WP_000443570.1 DUF1797 family protein -
  ACN076_RS08155 (ACN076_08155) clpE 1637789..1640047 (+) 2259 WP_420789809.1 AAA family ATPase Regulator
  ACN076_RS08160 (ACN076_08160) - 1640176..1640628 (+) 453 WP_420789810.1 NUDIX hydrolase -
  ACN076_RS08165 (ACN076_08165) - 1640687..1640986 (+) 300 WP_000767197.1 DUF1827 family protein -
  ACN076_RS08170 (ACN076_08170) ezrA 1641161..1642888 (-) 1728 WP_420789811.1 septation ring formation regulator EzrA -
  ACN076_RS08175 (ACN076_08175) gyrB 1642970..1644916 (-) 1947 WP_420789812.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83793.29 Da        Isoelectric Point: 5.3727

>NTDB_id=1111468 ACN076_RS08155 WP_420789809.1 1637789..1640047(+) (clpE) [Streptococcus sp. K0074]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSLNRGSAQTPPPSQEKSLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKIRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKDLKAVMTSKGKIQIKSAKKAEVKTSEKEV

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=1111468 ACN076_RS08155 WP_420789809.1 1637789..1640047(+) (clpE) [Streptococcus sp. K0074]
ATGCTTTGTCAAAACTGTAAAATCAATGACTCAACAATTCATCTTTATACCAATCTCAATGGAAAGCAAAAACAAATTGA
CCTCTGTCAAAACTGCTATAAGATTATCAAGACAGATCCTAACAATAGCCTCTTTAAAGGTATGACGGATCTGAACAATC
GTGACTTTGATCCTTTTGGTGATTTCTTCAATGATCTAAACAATTTCAGACCTTCTAACAACACTCCTCCTACTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAATGGCGGTTATGGCTCCCTAAATCGTGGATCTGCCCAAACTCCGCCACCTAG
CCAAGAAAAAAGCCTGCTGGAAGAATTTGGTATCAATGTAACTGAGATTGCCCGTCGTGGAGATATAGATCCCGTTATTG
GACGCGATGATGAGATTATCCGTGTCATCGAGATTCTCAATCGCAGAACCAAGAATAATCCTGTTCTTATCGGTGAACCT
GGTGTCGGAAAAACTGCCGTTGTCGAAGGCTTAGCTCAGAAAATCGTTGATGGCGATGTTCCACATAAACTACAAGGTAA
ACAAGTCATCCGTCTGGATGTAGTTAGCCTAGTTCAAGGAACGGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAGGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTCGGTGCTGGTTCTGCG
GGCGATGGCAATATGGATGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGGGAACTGCAACTGGTCGGTGCCACTAC
CCTCAATGAATACCGTATCATTGAAAAAGATGCCGCCCTAGAGCGTCGTATGCAACCTGTTAAGGTCGATGAACCAACGG
TGGAGGAAACAATCACTATCCTCAAAGGGATTCAAAAGAAATATGAAGACTACCACCACGTTCAATATACCGATGCTGCG
ATTGAAGCTGCTGCAACTCTTTCCAATCGTTACATCCAAGATCGCTTCTTACCTGACAAGGCTATTGACCTCTTAGATGA
AGCGGGTTCTAAGATGAACTTGACCTTGAATTTTGTAGATCCTAAAGTCATTGATCAGCGCTTGATTGAGGCTGAAAATC
TCAAATCTCAAGCTACACGGGAGGAAGATTTTGAGAAGGCCGCCTACTTCCGCGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAAGATACTCCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAGCAGAAAACCAA
TATCCCTGTTGGTGATTTGAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCTGAAGACCTCAAGTCTCATGTTATTG
GACAGGACGATGCAGTTGATAAGATAGCCAAGGCTATTCGCCGTAATCGTGTCGGTCTCGGTACCCCTAACCGCCCAATC
GGAAGCTTCCTTTTCGTTGGGCCAACCGGTGTCGGTAAGACAGAACTTTCCAAACAACTAGCTATCGAACTTTTTGGTTC
TGCTGACAGCATGATTCGCTTTGACATGAGTGAATACATGGAAAAACACAGTGTAGCTAAGTTGGTCGGTGCCCCTCCAG
GTTATGTTGGCTACGATGAGGCTGGGCAATTAACTGAAAAAATCCGTCGTAATCCCTACTCTCTTATTCTTCTGGATGAA
GTGGAAAAAGCCCACCCAGATGTTATGCATATGTTCCTCCAGGTCTTAGACGATGGTCGTTTGACAGATGGGCAAGGGCG
TACCGTCAGCTTTAAGGATGCCATTATTATCATGACCTCAAATGCAGGTACAGGTAAGGCCGAAGCCAGCGTTGGTTTCG
GGGCAGCTCGCGAAGGACGTACCAACTCTGTTCTTGGTGAACTCGGTAACTTCTTTAGCCCAGAATTTATGAACCGTTTT
GACGGCATTATTGAGTTCAAAGCTCTCAGCAAGGATAATCTCCTTCAGATCGTCGAGCTCATGCTAGCAGATGTTAACAA
GCGCCTCTCTAGCAACAATATCCATCTAGATGTAACGGACAAGGTCAAAGAAAAATTGGTTGATCTCGGCTATGATCCAA
AAATGGGAGCACGCCCACTTCGCCGCACTATTCAAGACTATATTGAAGACGCAATCACTGACTACTACCTTGAAAATCCA
AGTGAAAAAGACCTCAAGGCAGTGATGACCAGCAAGGGCAAGATTCAAATTAAGTCTGCCAAAAAAGCTGAAGTAAAAAC
TTCTGAAAAAGAAGTATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-723)

AAA lid domain (AAA_lid_9)

(293-390)

ATPase family associated with various cellular activities (AAA) (AAA)

(155-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

98.136

99.867

0.98
  clpE Streptococcus pneumoniae D39

98.136

99.867

0.98
  clpE Streptococcus pneumoniae R6

98.136

99.867

0.98
  clpE Streptococcus pneumoniae TIGR4

98.003

99.867

0.979
  clpE Streptococcus mutans UA159

83.2

99.734

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

75.099

100

0.758
  clpC Bacillus subtilis subsp. subtilis str. 168

50.359

92.686

0.467
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.687

83.378

0.398
  clpC Streptococcus pneumoniae Rx1

46.975

83.511

0.392
  clpC Streptococcus pneumoniae D39

46.975

83.511

0.392
  clpC Streptococcus pneumoniae TIGR4

46.975

83.511

0.392
  clpC Streptococcus mutans UA159

46.571

83.378

0.388
  clpC Streptococcus thermophilus LMD-9

46.474

82.979

0.386
  clpC Streptococcus thermophilus LMG 18311

46.08

83.112

0.383

Multiple sequence alignment