Detailed information NTG1111428

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACN076_RS01605
• Genome accession: NZ_CP184836
• Coordinates: 285486..287918 (+)
• Length: 810 a.a.
• NCBI ID: WP_420790015.1
• Uniprot ID: -
• Organism: Streptococcus sp. K0074
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 280486..292918

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS01570 (ACN076_01570)	-	280689..280850 (+)	162	WP_192851990.1	hypothetical protein	-
ACN076_RS01575 (ACN076_01575)	-	280940..281170 (+)	231	WP_084926971.1	hypothetical protein	-
ACN076_RS01580 (ACN076_01580)	-	281219..282079 (+)	861	WP_084926972.1	phage major capsid protein	-
ACN076_RS01585 (ACN076_01585)	-	282089..282637 (+)	549	WP_420790013.1	hypothetical protein	-
ACN076_RS01590 (ACN076_01590)	-	283015..283425 (+)	411	WP_261038979.1	DUF722 domain-containing protein	-
ACN076_RS01595 (ACN076_01595)	-	283604..284707 (-)	1104	WP_084926975.1	hypothetical protein	-
ACN076_RS01600 (ACN076_01600)	-	285026..285484 (+)	459	WP_420790014.1	CtsR family transcriptional regulator	-
ACN076_RS01605 (ACN076_01605)	clpC	285486..287918 (+)	2433	WP_420790015.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACN076_RS01610 (ACN076_01610)	-	287990..288187 (-)	198	WP_239683522.1	hypothetical protein	-
ACN076_RS01615 (ACN076_01615)	-	288498..289196 (+)	699	WP_420790016.1	hypothetical protein	-
ACN076_RS01620 (ACN076_01620)	-	289267..289818 (-)	552	WP_420790017.1	cysteine hydrolase family protein	-
ACN076_RS01625 (ACN076_01625)	dusB	289820..290800 (-)	981	WP_000183308.1	tRNA dihydrouridine synthase DusB	-
ACN076_RS01630 (ACN076_01630)	hslO	290787..291659 (-)	873	WP_420790018.1	Hsp33 family molecular chaperone HslO	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90265.93 Da
• Isoelectric Point: 5.7593

>NTDB_id=1111428 ACN076_RS01605 WP_420790015.1 285486..287918(+) (clpC) [Streptococcus sp. K0074]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDGNALAARILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKALMDGKWKQAAQLIEKEEQVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVKPLVVSLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELESGSTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=1111428 ACN076_RS01605 WP_420790015.1 285486..287918(+) (clpC) [Streptococcus sp. K0074]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGCCATTTTGGAGCTCGTTACCTAGA
GTCTTGGCACTTGTTGATTGCCATGTCCAATCACAGTTATAGTGTGGCAGGGGCAACTTTAAATGATTATCCATATGAGA
TGGACCGTTTAGAAGAAGTAGCTTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTT
TCTCATCGTTTGCAGGTTCTTTTTGATGAAGCAGAGTATGTAGCGTCAGTGGTCCATGCTAAGGTGTTAGGGACAGAGCA
TGTTCTCTATGCGATTTTGCATGATGGTAATGCCTTGGCGGCTCGTATCTTGGAGAGAGCTGGTTTTTCTTATGAAGATA
AGAAAGATCAGGTCAAGATTGCTGCCCTACGTCGAAATCTAGAAGAACGTGCAGGCTGGACTCGTGAAGACCTCAAGGCT
CTACGCCAACGCCATCGTACAGTGGCTGACAAGCAAAATTCTATGGCTAATATGATGGGGATGCCCCAGACTCCGAGTGG
TGGTCTCGAGGACTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATCGGTCGGGATAAGG
AAATCTCGCGTATGATTCAAATTTTGAGCCGTAAAACCAAGAATAATCCTGTTTTGGTTGGGGATGCTGGTGTCGGGAAA
ACAGCCTTGGCGCTTGGGCTCGCTCAGCGTATTGCTAGTGGAGATGTACCTGCGGAAATGGCTAAGATGCGCGTGTTAGA
GCTTGATTTGATGAATGTCGTGGCAGGGACACGCTTCCGTGGTGACTTTGAAGAACGCATGAATAATATCATCAAGGATA
TTGAAGAAGATGGGCAAGTCATCCTCTTTATCGATGAACTTCACACTATCATGGGTTCTGGGAGCGGGATTGATTCGACT
CTGGATGCGGCCAATATCTTGAAGCCAGCCTTGGCGCGTGGAACTTTGAGAACGGTTGGTGCGACCACTCAGGAAGAATA
TCAAAAACATATCGAAAAAGATGCAGCCCTTTCTCGTCGTTTCGCCAAAGTGACGATTGAAGAGCCAAGTGTGGCAGACA
GCATGACCATTTTGCAAGGCTTGAAGGCGACTTATGAGAAACATCACCGGGTGCAAATCACAGATGAAGCGGTTGAAACA
GCCGTCAAGATGGCTCATCGTTACTTGACTAGTCGCCATTTGCCAGACTCTGCTATCGACCTCTTGGATGAGGCAGCAGC
AACAGTGCAAAATAAATCAAAGCATGTAAAAGCAGACGATTCTGACTTGAGTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAGGCAGCTCAGCTAATTGAAAAAGAAGAGCAAGTGCCTGTCTACAAAGACTTGGTGACAGAGTCTGATATT
TTGACCACCTTGAGTCGCTTATCAGGTATTCCAGTCCAAAAACTGACGCAAACAGATGCTAAGAAATACCTAAATCTTGA
AGCTGAACTACACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCGATTCGCCGCAATCAGTCAG
GGATTCGCAGTCATAAGCGCCCGATTGGTTCCTTTATGTTCCTAGGGCCTACAGGTGTCGGTAAGACCGAATTGGCCAAG
GCTCTGGCAGAAGTTCTTTTTGATGATGAATCAGCTCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
TAGCCGACTCAATGGAGCTCCTCCGGGCTATGTGGGTTATGAAGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAACAAAC
CATACTCCGTTCTCCTCTTTGACGAGGTAGAAAAAGCCCACCCAGACATCTTTAATGTTCTCTTGCAGGTCTTGGATGAC
GGTGTCTTGACCGATAGTAAGGGACGCAAGGTTGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
AGCCCTTCGTGATGACAAGACAGTTGGATTTGGGGCAAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT
TTGAAGAGCTGAAAAAAGCTTATAGACCTGAGTTTATTAACCGTATTGATGAAAAGGTGGTCTTCCATAGCCTGTCTAGC
GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAACCTTTAGTGGTAAGTTTGGCTGAAAAAGGTATTGACTTGAAATT
ACAAGCTTCCGCACTGAAATTGTTGGCAAATCAAGGATATGACCCAGAGATGGGAGCTCGTCCACTTCGCAGAACCCTAC
AAACAGAAGTGGAAGACAAGTTGGCAGAACTTCTTCTCAAGGGAGAATTAGAGTCAGGCAGCACACTTAAGATTGGTGTT
AAAGCAGGCCAGTTAAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-139)

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-798)

• AAA lid domain (AAA_lid_9) (370-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	98.642	100	0.986
clpC	Streptococcus pneumoniae D39	98.642	100	0.986
clpC	Streptococcus pneumoniae TIGR4	98.642	100	0.986
clpC	Streptococcus mutans UA159	66.913	100	0.672
clpC	Streptococcus thermophilus LMD-9	66.216	100	0.665
clpC	Streptococcus thermophilus LMG 18311	66.093	100	0.664
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.733	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	45.859	99.877	0.458
clpE	Streptococcus mutans UA159	48.796	76.914	0.375
clpE	Streptococcus pneumoniae Rx1	46.614	78.395	0.365
clpE	Streptococcus pneumoniae D39	46.614	78.395	0.365
clpE	Streptococcus pneumoniae R6	46.614	78.395	0.365
clpE	Streptococcus pneumoniae TIGR4	46.614	78.395	0.365