Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   ACKTT6_RS07720 Genome accession   NZ_AP038759
Coordinates   1644628..1645977 (+) Length   449 a.a.
NCBI ID   WP_176430037.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain BG-PG180     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 1628745..1647627 1644628..1645977 within 0


Gene organization within MGE regions


Location: 1628745..1647627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTT6_RS07655 (BGPG180_14820) ccrB 1628745..1630370 (+) 1626 WP_254104479.1 cassette chromosome recombinase CcrB Machinery gene
  ACKTT6_RS07660 (BGPG180_14830) - 1630497..1631114 (+) 618 WP_002487818.1 hypothetical protein -
  ACKTT6_RS07665 (BGPG180_14840) - 1631654..1632004 (+) 351 WP_002487822.1 SAUGI family uracil-DNA glycosylase inhibitor -
  ACKTT6_RS07670 (BGPG180_14850) - 1632091..1632402 (+) 312 WP_002487841.1 DUF960 family protein -
  ACKTT6_RS07675 (BGPG180_14860) - 1632417..1632920 (+) 504 WP_032604766.1 DUF1643 domain-containing protein -
  ACKTT6_RS07680 (BGPG180_14870) - 1632935..1633156 (+) 222 WP_002487836.1 hypothetical protein -
  ACKTT6_RS07685 (BGPG180_14880) - 1633275..1634081 (+) 807 WP_002487840.1 site-specific DNA-methyltransferase -
  ACKTT6_RS07690 (BGPG180_14890) - 1634078..1634896 (+) 819 WP_002487821.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ACKTT6_RS07695 (BGPG180_14900) - 1634921..1636936 (-) 2016 WP_002487819.1 hypothetical protein -
  ACKTT6_RS07700 (BGPG180_14910) - 1637261..1639474 (-) 2214 WP_031880885.1 S8 family peptidase -
  ACKTT6_RS07705 (BGPG180_14920) - 1639467..1640516 (-) 1050 WP_031880884.1 ATP-binding protein -
  ACKTT6_RS07710 (BGPG180_14930) - 1641057..1642487 (+) 1431 WP_031880883.1 DUF6038 family protein -
  ACKTT6_RS07715 (BGPG180_14940) cch1 1642607..1644394 (+) 1788 WP_031880882.1 cassette chromosome replicative helicase -
  ACKTT6_RS07720 (BGPG180_14950) ccrA 1644628..1645977 (+) 1350 WP_176430037.1 cassette chromosome recombinase CcrA Machinery gene
  ACKTT6_RS07725 (BGPG180_14960) ccrB 1645999..1647627 (+) 1629 WP_176430038.1 cassette chromosome recombinase CcrB Machinery gene

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52605.32 Da        Isoelectric Point: 9.9534

>NTDB_id=111099 ACKTT6_RS07720 WP_176430037.1 1644628..1645977(+) (ccrA) [Staphylococcus epidermidis strain BG-PG180]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNLNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDHHIYAKIKNAIDKRLKRQRNTETHHTLTQEKLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=111099 ACKTT6_RS07720 WP_176430037.1 1644628..1645977(+) (ccrA) [Staphylococcus epidermidis strain BG-PG180]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACTTGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCACCATATCTACGCAAAAATTAAAAATGCGATTGACAAACGCTTAAAAAGACAACGAAA
CACAGAAACACATCACACACTGACTCAAGAAAAACTAATAGAAAAGTTAGCCCAAGGCATCATCGATGCAGAAACGTTCA
GAAAACAAATGCAATCATTACATCAACAACCGCAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTGAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Recombinase (Recombinase)

(169-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.1

100

0.951
  ccrA Staphylococcus aureus COL

73.719

100

0.737

Multiple sequence alignment