Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACNR93_RS02805 Genome accession   NZ_CP184736
Coordinates   534747..537032 (-) Length   761 a.a.
NCBI ID   WP_420543853.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 529747..542032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS02785 (ACNR93_02785) - 529766..530530 (+) 765 WP_021141864.1 DivIVA domain-containing protein -
  ACNR93_RS02790 (ACNR93_02790) ileS 530862..533660 (+) 2799 WP_024344235.1 isoleucine--tRNA ligase -
  ACNR93_RS02795 (ACNR93_02795) - 533749..534051 (-) 303 WP_004230746.1 DUF1827 family protein -
  ACNR93_RS02800 (ACNR93_02800) - 534124..534570 (-) 447 WP_024344236.1 NUDIX hydrolase -
  ACNR93_RS02805 (ACNR93_02805) clpE 534747..537032 (-) 2286 WP_420543853.1 AAA family ATPase Regulator
  ACNR93_RS02810 (ACNR93_02810) - 537314..537499 (-) 186 WP_420543854.1 helix-turn-helix transcriptional regulator -
  ACNR93_RS02815 (ACNR93_02815) argF 537668..538642 (+) 975 WP_074483322.1 ornithine carbamoyltransferase -
  ACNR93_RS02820 (ACNR93_02820) - 538765..538995 (+) 231 WP_004230761.1 DUF1797 family protein -
  ACNR93_RS02825 (ACNR93_02825) - 539225..539911 (+) 687 WP_420543855.1 amino acid ABC transporter permease -
  ACNR93_RS02830 (ACNR93_02830) - 539911..540645 (+) 735 WP_420543856.1 amino acid ABC transporter ATP-binding protein -
  ACNR93_RS02835 (ACNR93_02835) - 541007..541483 (+) 477 WP_045798142.1 FeoA family protein -

Sequence

Protein


Download         Length: 761 a.a.        Molecular weight: 84451.50 Da        Isoelectric Point: 4.8733

>NTDB_id=1110940 ACNR93_RS02805 WP_420543853.1 534747..537032(-) (clpE) [Streptococcus equinus strain NM-2-29]
MLCQNCHLNESTIHLYTNVNGQQRQIDLCQNCYQIMKTDPNNAILGGLGGNSQPTSNATNQSTNPFDDFFSNLGGFPAFG
GQGFQNTPPTQPGGGNNGRGGNGNGNFRQGAQVQQQEPKGLLEEFGINVTDIARRGDIDPVVGRDSEIIRVIEILNRRTK
NNPVLIGEPGVGKTAVVEGLAQKIVDGNVPQKLQNKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRERKDVILFIDEI
HEIVGAGNAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILRGIQKKYEDY
HHVKYSDDAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIQAENLKTQATRDEDYERAAYFR
DQIAKYKEMQKQTIDEDDIPVITEKTIEAIVEEKTNIPVGDLKEKEQSQLIHLADDLKEHVIGQDEAVDKIAKAIRRNRV
GLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRN
PYSLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGQLGDF
FSPEFMNRFDGIIEFKALSKDNLLQIVNIMLDDVNKRLATNDIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDA
ITDFYLEHPTEKDLKAVMTSNGKIIIKSAKKVETEESVSAE

Nucleotide


Download         Length: 2286 bp        

>NTDB_id=1110940 ACNR93_RS02805 WP_420543853.1 534747..537032(-) (clpE) [Streptococcus equinus strain NM-2-29]
ATGCTCTGTCAGAATTGTCATTTAAACGAATCAACAATTCACCTGTATACAAATGTTAATGGTCAGCAAAGACAAATTGA
TTTGTGCCAAAACTGCTATCAAATCATGAAAACTGACCCAAATAACGCTATCTTAGGAGGTTTGGGTGGAAATTCTCAAC
CAACCTCTAACGCAACTAATCAATCCACAAATCCTTTCGATGATTTCTTTAGCAATCTCGGTGGCTTCCCTGCATTTGGA
GGTCAAGGATTTCAAAATACCCCTCCAACACAACCTGGTGGAGGAAATAATGGACGTGGCGGCAACGGAAATGGCAACTT
CCGTCAAGGCGCTCAAGTTCAACAACAAGAGCCAAAAGGCTTGTTAGAAGAATTCGGTATCAACGTCACTGATATTGCAC
GACGTGGTGATATCGACCCTGTTGTGGGACGTGATTCTGAAATCATTCGAGTTATCGAAATTCTTAACCGCCGTACAAAA
AACAACCCAGTTTTGATTGGTGAACCTGGTGTTGGTAAAACAGCTGTTGTTGAAGGGCTCGCTCAAAAAATCGTTGATGG
TAACGTTCCTCAAAAACTCCAAAACAAACAAGTCATTCGTCTCGATGTCGTAAGCCTTGTTCAAGGGACTGGTATCCGTG
GACAATTTGAAGAACGCATGCAAAAACTCATGGAAGAAATTCGTGAACGCAAAGACGTAATTTTGTTTATCGATGAAATC
CATGAAATTGTTGGTGCTGGTAATGCTGGCGATGGTAATATGGATGCTGGTAACATTTTAAAACCAGCTCTTGCACGTGG
TGAATTACAATTAGTTGGTGCTACTACTCTTAACGAATACCGTATTATCGAAAAAGATGCAGCACTTGAACGTCGTATGC
AACCTGTAAAAGTTGACGAACCAAGTGTTGAAGAAACTATTACAATTCTTCGTGGTATTCAAAAGAAATATGAAGACTAT
CACCATGTCAAATATAGCGATGATGCTATCGAAGCTGCTGCCAACCTCTCAAATCGCTACATCCAAGACCGCTTCCTTCC
AGATAAGGCAATCGACTTGCTTGATGAAGCAGGTTCTAAGATGAACTTGACACTCAACTTTGTTGATCCAAAAGAGATTG
ACAAGCGTTTGATTCAAGCTGAAAATCTAAAAACACAAGCTACTCGCGATGAAGACTATGAACGCGCAGCTTATTTCCGT
GATCAAATCGCAAAATACAAAGAAATGCAAAAACAAACGATTGACGAAGATGACATCCCAGTGATTACCGAAAAGACCAT
CGAAGCCATCGTTGAAGAAAAAACAAATATCCCTGTTGGTGATTTGAAAGAAAAAGAACAATCACAATTAATTCACCTTG
CTGATGACTTGAAAGAGCACGTTATCGGCCAAGATGAAGCCGTTGATAAGATTGCCAAAGCCATCCGCCGTAACCGTGTT
GGACTTGGCACACCAAATCGACCAATTGGTTCATTCCTCTTTGTCGGACCAACCGGTGTTGGTAAAACAGAACTTTCAAA
ACAACTAGCAATTGAACTCTTTGGTTCAGCTGACAGCATGATTCGCTTTGACATGTCTGAATACATGGAAAAACACGCTG
TCGCTAAACTTGTCGGAGCTCCTCCAGGATATGTTGGTTACGAAGAAGCTGGTCAATTGACTGAAAAAGTTCGTCGTAAT
CCATACTCACTCATTCTTCTTGATGAAGTTGAAAAAGCACACCCTGACGTTATGCATATGTTCTTGCAAGTACTTGATGA
TGGTCGTTTGACTGACGGGCAAGGTCGTACAGTAAGCTTTAAGGATACTATTATCATCATGACTTCAAATGCTGGTACTG
GTAAAGCTGAAGCCTCTGTTGGTTTTGGTGCTGCTCGTGAAGGTCGAACTAATTCCGTTCTTGGTCAACTTGGTGATTTC
TTCAGCCCAGAATTTATGAACCGTTTTGACGGCATCATCGAATTCAAAGCCCTTAGCAAGGACAATCTTCTTCAAATCGT
AAACATCATGCTTGATGATGTTAATAAACGTTTAGCTACAAATGATATTCATCTTGATGTCACAGACAAAGTTAAAGAAA
AACTTGTCGATCTTGGATATGATCCTAAGATGGGAGCTCGTCCGCTTCGTCGAACTATTCAAGATTACATCGAAGATGCC
ATCACTGACTTCTATCTTGAACACCCAACTGAAAAAGATTTAAAAGCCGTGATGACAAGTAATGGTAAGATCATCATTAA
ATCAGCTAAAAAAGTTGAAACCGAAGAATCTGTTTCAGCAGAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-732)

ATPase family associated with various cellular activities (AAA) (AAA)

(164-283)

AAA lid domain (AAA_lid_9)

(302-399)

AAA domain (Cdc48 subfamily) (AAA_2)

(487-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.43

99.212

0.848
  clpE Streptococcus pneumoniae Rx1

82.895

99.869

0.828
  clpE Streptococcus pneumoniae D39

82.895

99.869

0.828
  clpE Streptococcus pneumoniae R6

82.895

99.869

0.828
  clpE Streptococcus pneumoniae TIGR4

82.895

99.869

0.828
  clpC Lactococcus lactis subsp. cremoris KW2

76.741

100

0.767
  clpC Bacillus subtilis subsp. subtilis str. 168

50.82

88.173

0.448
  clpC Streptococcus pneumoniae Rx1

47.917

81.997

0.393
  clpC Streptococcus pneumoniae D39

47.917

81.997

0.393
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.84

82.129

0.393
  clpC Streptococcus pneumoniae TIGR4

47.756

81.997

0.392
  clpC Streptococcus thermophilus LMD-9

46.166

83.968

0.388
  clpC Streptococcus thermophilus LMG 18311

45.853

83.968

0.385
  clpC Streptococcus mutans UA159

47.021

81.603

0.384

Multiple sequence alignment