Detailed information NTG1110909

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HQV14_RS09615
• Genome accession: NZ_CP184730
• Coordinates: 1947961..1949004 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B0419
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1942961..1954004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQV14_RS09585 (HQV14_09585)	-	1943383..1944639 (-)	1257	WP_001793428.1	aminopeptidase	-
HQV14_RS09590 (HQV14_09590)	-	1944642..1944842 (-)	201	WP_000180463.1	DUF1128 family protein	-
HQV14_RS09595 (HQV14_09595)	-	1944989..1945453 (+)	465	WP_420542359.1	low molecular weight protein-tyrosine-phosphatase	-
HQV14_RS09600 (HQV14_09600)	-	1945460..1945735 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HQV14_RS09605 (HQV14_09605)	-	1946013..1947230 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
HQV14_RS09610 (HQV14_09610)	vraR	1947342..1947971 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
HQV14_RS09615 (HQV14_09615)	vraS	1947961..1949004 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HQV14_RS09620 (HQV14_09620)	liaF	1949001..1949702 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HQV14_RS09625 (HQV14_09625)	-	1949717..1950103 (-)	387	WP_001110179.1	hypothetical protein	-
HQV14_RS09630 (HQV14_09630)	map	1950320..1951078 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
HQV14_RS09635 (HQV14_09635)	-	1951609..1952595 (+)	987	WP_031811349.1	FUSC family protein	-
HQV14_RS09640 (HQV14_09640)	-	1953026..1953439 (-)	414	WP_001549145.1	hypothetical protein	-
HQV14_RS09645 (HQV14_09645)	-	1953468..1953578 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1110909 HQV14_RS09615 WP_001017131.1 1947961..1949004(-) (vraS) [Staphylococcus aureus strain B0419]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1110909 HQV14_RS09615 WP_001017131.1 1947961..1949004(-) (vraS) [Staphylococcus aureus strain B0419]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1