Detailed information NTG0111089

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACKTT6_RS03390
• Genome accession: NZ_AP038759
• Coordinates: 721754..722800 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain BG-PG180
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 716754..727800

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKTT6_RS03360 (BGPG180_06340)	-	717138..718379 (-)	1242	WP_002457094.1	aminopeptidase	-
ACKTT6_RS03365 (BGPG180_06350)	-	718381..718596 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ACKTT6_RS03370 (BGPG180_06360)	-	718737..719201 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACKTT6_RS03375 (BGPG180_06370)	-	719209..719493 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
ACKTT6_RS03380 (BGPG180_06380)	-	719900..721078 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
ACKTT6_RS03385 (BGPG180_06390)	vraR	721135..721764 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
ACKTT6_RS03390 (BGPG180_06400)	vraS	721754..722800 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
ACKTT6_RS03395 (BGPG180_06410)	liaF	722797..723498 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
ACKTT6_RS03400 (BGPG180_06420)	-	723513..723899 (-)	387	WP_001830382.1	hypothetical protein	-
ACKTT6_RS03405 (BGPG180_06430)	map	724057..724812 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
ACKTT6_RS03410 (BGPG180_06440)	-	724986..725972 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
ACKTT6_RS03415 (BGPG180_06450)	isaB	726123..726659 (-)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=111089 ACKTT6_RS03390 WP_001830374.1 721754..722800(-) (vraS) [Staphylococcus epidermidis strain BG-PG180]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=111089 ACKTT6_RS03390 WP_001830374.1 721754..722800(-) (vraS) [Staphylococcus epidermidis strain BG-PG180]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92