Detailed information NTG1110824

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HQV19_RS13625
• Genome accession: NZ_CP184719
• Coordinates: 2704182..2705069 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain B0483
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2699182..2710069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQV19_RS13595 (HQV19_13595)	-	2699201..2699293 (+)	93	WP_010956583.1	hypothetical protein	-
HQV19_RS13600 (HQV19_13600)	-	2699401..2699898 (-)	498	WP_001065268.1	glutathione peroxidase	-
HQV19_RS13605 (HQV19_13605)	-	2699908..2700168 (-)	261	WP_001789910.1	hypothetical protein	-
HQV19_RS13610 (HQV19_13610)	-	2700550..2700663 (-)	114	WP_001791776.1	hypothetical protein	-
HQV19_RS13615 (HQV19_13615)	-	2701322..2703322 (-)	2001	WP_000776751.1	ABC transporter permease	-
HQV19_RS13620 (HQV19_13620)	-	2703319..2704074 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HQV19_RS13625 (HQV19_13625)	braS	2704182..2705069 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HQV19_RS13630 (HQV19_13630)	braR	2705080..2705745 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HQV19_RS13635 (HQV19_13635)	-	2705771..2705971 (-)	201	WP_000604728.1	hypothetical protein	-
HQV19_RS13640 (HQV19_13640)	-	2706169..2707593 (+)	1425	WP_000953744.1	alkaline phosphatase	-
HQV19_RS13645 (HQV19_13645)	-	2707653..2707754 (-)	102	WP_000731972.1	SE2200 family small protein	-
HQV19_RS13650 (HQV19_13650)	-	2707876..2708331 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HQV19_RS13655 (HQV19_13655)	-	2708576..2709337 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1110824 HQV19_RS13625 WP_000143419.1 2704182..2705069(-) (braS) [Staphylococcus aureus strain B0483]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1110824 HQV19_RS13625 WP_000143419.1 2704182..2705069(-) (braS) [Staphylococcus aureus strain B0483]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997