Detailed information NTG1110819

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HQV19_RS09700
• Genome accession: NZ_CP184719
• Coordinates: 1960435..1961478 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B0483
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1955435..1966478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQV19_RS09670 (HQV19_09670)	-	1955853..1957109 (-)	1257	WP_001795438.1	aminopeptidase	-
HQV19_RS09675 (HQV19_09675)	-	1957112..1957312 (-)	201	WP_000180461.1	DUF1128 family protein	-
HQV19_RS09680 (HQV19_09680)	-	1957459..1957923 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HQV19_RS09685 (HQV19_09685)	-	1957930..1958205 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HQV19_RS09690 (HQV19_09690)	-	1958483..1959700 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
HQV19_RS09695 (HQV19_09695)	vraR	1959816..1960445 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
HQV19_RS09700 (HQV19_09700)	vraS	1960435..1961478 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HQV19_RS09705 (HQV19_09705)	liaF	1961475..1962176 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HQV19_RS09710 (HQV19_09710)	-	1962191..1962577 (-)	387	WP_001110179.1	hypothetical protein	-
HQV19_RS09715 (HQV19_09715)	map	1962794..1963552 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HQV19_RS09720 (HQV19_09720)	-	1964080..1965066 (+)	987	WP_000999713.1	FUSC family protein	-
HQV19_RS09725 (HQV19_09725)	-	1965556..1965969 (-)	414	WP_001549145.1	hypothetical protein	-
HQV19_RS09730 (HQV19_09730)	-	1965998..1966108 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1110819 HQV19_RS09700 WP_001017131.1 1960435..1961478(-) (vraS) [Staphylococcus aureus strain B0483]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1110819 HQV19_RS09700 WP_001017131.1 1960435..1961478(-) (vraS) [Staphylococcus aureus strain B0483]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1