Detailed information NTG1110784

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HQV16_RS13060
• Genome accession: NZ_CP184713
• Coordinates: 2626108..2626995 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain B0421
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2621108..2631995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQV16_RS13030 (HQV16_13030)	-	2621127..2621219 (+)	93	WP_010956583.1	hypothetical protein	-
HQV16_RS13035 (HQV16_13035)	-	2621327..2621824 (-)	498	WP_001065268.1	glutathione peroxidase	-
HQV16_RS13040 (HQV16_13040)	-	2621834..2622094 (-)	261	WP_001791974.1	hypothetical protein	-
HQV16_RS13045 (HQV16_13045)	-	2622476..2622589 (-)	114	Protein_2529	hypothetical protein	-
HQV16_RS13050 (HQV16_13050)	-	2623248..2625248 (-)	2001	WP_000776751.1	ABC transporter permease	-
HQV16_RS13055 (HQV16_13055)	-	2625245..2626000 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HQV16_RS13060 (HQV16_13060)	braS	2626108..2626995 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HQV16_RS13065 (HQV16_13065)	braR	2627006..2627671 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HQV16_RS13070 (HQV16_13070)	-	2627697..2627897 (-)	201	WP_000604730.1	hypothetical protein	-
HQV16_RS13075 (HQV16_13075)	-	2628095..2629519 (+)	1425	WP_000953755.1	alkaline phosphatase	-
HQV16_RS13080 (HQV16_13080)	-	2629579..2629680 (-)	102	WP_000731976.1	SE2200 family small protein	-
HQV16_RS13085 (HQV16_13085)	-	2629802..2630257 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HQV16_RS13090 (HQV16_13090)	-	2630502..2631263 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1110784 HQV16_RS13060 WP_000143425.1 2626108..2626995(-) (braS) [Staphylococcus aureus strain B0421]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1110784 HQV16_RS13060 WP_000143425.1 2626108..2626995(-) (braS) [Staphylococcus aureus strain B0421]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1