Detailed information NTG1110657

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HQU66_RS13360
• Genome accession: NZ_CP184655
• Coordinates: 2672833..2673720 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain B0356
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2667833..2678720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQU66_RS13330 (HQU66_13330)	-	2667852..2667944 (+)	93	WP_010956583.1	hypothetical protein	-
HQU66_RS13335 (HQU66_13335)	-	2668052..2668549 (-)	498	WP_001065268.1	glutathione peroxidase	-
HQU66_RS13340 (HQU66_13340)	-	2668559..2668819 (-)	261	WP_001789910.1	hypothetical protein	-
HQU66_RS13345 (HQU66_13345)	-	2669201..2669314 (-)	114	WP_001791776.1	hypothetical protein	-
HQU66_RS13350 (HQU66_13350)	-	2669973..2671973 (-)	2001	WP_000776751.1	ABC transporter permease	-
HQU66_RS13355 (HQU66_13355)	-	2671970..2672725 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HQU66_RS13360 (HQU66_13360)	braS	2672833..2673720 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HQU66_RS13365 (HQU66_13365)	braR	2673731..2674396 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HQU66_RS13370 (HQU66_13370)	-	2674422..2674622 (-)	201	WP_000604728.1	hypothetical protein	-
HQU66_RS13375 (HQU66_13375)	-	2674820..2676244 (+)	1425	WP_000953744.1	alkaline phosphatase	-
HQU66_RS13380 (HQU66_13380)	-	2676304..2676405 (-)	102	WP_000731972.1	SE2200 family small protein	-
HQU66_RS13385 (HQU66_13385)	-	2676527..2676982 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HQU66_RS13390 (HQU66_13390)	-	2677227..2677988 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1110657 HQU66_RS13360 WP_000143419.1 2672833..2673720(-) (braS) [Staphylococcus aureus strain B0356]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1110657 HQU66_RS13360 WP_000143419.1 2672833..2673720(-) (braS) [Staphylococcus aureus strain B0356]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997