Detailed information NTG1110652

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HQU66_RS09445
• Genome accession: NZ_CP184655
• Coordinates: 1930937..1931980 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B0356
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1925937..1936980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQU66_RS09415 (HQU66_09415)	-	1926355..1927611 (-)	1257	WP_001795438.1	aminopeptidase	-
HQU66_RS09420 (HQU66_09420)	-	1927614..1927814 (-)	201	WP_000180461.1	DUF1128 family protein	-
HQU66_RS09425 (HQU66_09425)	-	1927961..1928425 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HQU66_RS09430 (HQU66_09430)	-	1928432..1928707 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HQU66_RS09435 (HQU66_09435)	-	1928985..1930202 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
HQU66_RS09440 (HQU66_09440)	vraR	1930318..1930947 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
HQU66_RS09445 (HQU66_09445)	vraS	1930937..1931980 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HQU66_RS09450 (HQU66_09450)	liaF	1931977..1932678 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HQU66_RS09455 (HQU66_09455)	-	1932693..1933079 (-)	387	WP_001110179.1	hypothetical protein	-
HQU66_RS09460 (HQU66_09460)	map	1933296..1934054 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HQU66_RS09465 (HQU66_09465)	-	1934582..1935568 (+)	987	WP_000999713.1	FUSC family protein	-
HQU66_RS09470 (HQU66_09470)	-	1936058..1936471 (-)	414	WP_001549145.1	hypothetical protein	-
HQU66_RS09475 (HQU66_09475)	-	1936500..1936610 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1110652 HQU66_RS09445 WP_001017131.1 1930937..1931980(-) (vraS) [Staphylococcus aureus strain B0356]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1110652 HQU66_RS09445 WP_001017131.1 1930937..1931980(-) (vraS) [Staphylococcus aureus strain B0356]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1