Detailed information NTG1109692

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJD_RS10795
• Genome accession: NZ_CP184567
• Coordinates: 2181939..2182826 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CBTW2018008
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2176939..2187826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJD_RS10765 (ACOCJD_10765)	-	2177672..2178433 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCJD_RS10770 (ACOCJD_10770)	-	2178677..2179132 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJD_RS10775 (ACOCJD_10775)	-	2179254..2179355 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJD_RS10780 (ACOCJD_10780)	-	2179415..2180839 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJD_RS10785 (ACOCJD_10785)	-	2181037..2181237 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJD_RS10790 (ACOCJD_10790)	braR	2181263..2181928 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJD_RS10795 (ACOCJD_10795)	braS	2181939..2182826 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJD_RS10800 (ACOCJD_10800)	-	2182934..2183689 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJD_RS10805 (ACOCJD_10805)	-	2183686..2185686 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJD_RS10810 (ACOCJD_10810)	-	2186355..2186468 (+)	114	WP_014937089.1	hypothetical protein	-
ACOCJD_RS10815 (ACOCJD_10815)	-	2186850..2187110 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJD_RS10820 (ACOCJD_10820)	-	2187120..2187617 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJD_RS10825 (ACOCJD_10825)	-	2187725..2187817 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109692 ACOCJD_RS10795 WP_000143420.1 2181939..2182826(+) (braS) [Staphylococcus aureus strain CBTW2018008]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109692 ACOCJD_RS10795 WP_000143420.1 2181939..2182826(+) (braS) [Staphylococcus aureus strain CBTW2018008]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993