Detailed information NTG1109647

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJA_RS10760
• Genome accession: NZ_CP184565
• Coordinates: 2178826..2179713 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CBTW2018043
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2173826..2184713

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJA_RS10730 (ACOCJA_10730)	-	2174559..2175320 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCJA_RS10735 (ACOCJA_10735)	-	2175564..2176019 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJA_RS10740 (ACOCJA_10740)	-	2176141..2176242 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJA_RS10745 (ACOCJA_10745)	-	2176302..2177726 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJA_RS10750 (ACOCJA_10750)	-	2177924..2178124 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJA_RS10755 (ACOCJA_10755)	braR	2178150..2178815 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJA_RS10760 (ACOCJA_10760)	braS	2178826..2179713 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJA_RS10765 (ACOCJA_10765)	-	2179821..2180576 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJA_RS10770 (ACOCJA_10770)	-	2180573..2182573 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJA_RS10775 (ACOCJA_10775)	-	2183242..2183355 (+)	114	WP_014937089.1	hypothetical protein	-
ACOCJA_RS10780 (ACOCJA_10780)	-	2183737..2183997 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJA_RS10785 (ACOCJA_10785)	-	2184007..2184504 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJA_RS10790 (ACOCJA_10790)	-	2184612..2184704 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109647 ACOCJA_RS10760 WP_000143420.1 2178826..2179713(+) (braS) [Staphylococcus aureus strain CBTW2018043]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109647 ACOCJA_RS10760 WP_000143420.1 2178826..2179713(+) (braS) [Staphylococcus aureus strain CBTW2018043]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993