Detailed information NTG1109574

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACOCI8_RS06500
• Genome accession: NZ_CP184563
• Coordinates: 1313335..1314378 (+)
• Length: 347 a.a.
• NCBI ID: WP_096777928.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain SCTW2018065
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1308335..1319378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCI8_RS06470 (ACOCI8_06470)	-	1308950..1309060 (+)	111	WP_014937049.1	hypothetical protein	-
ACOCI8_RS06475 (ACOCI8_06475)	-	1309089..1309502 (+)	414	WP_025174370.1	hypothetical protein	-
ACOCI8_RS06480 (ACOCI8_06480)	-	1309691..1310677 (-)	987	WP_000999712.1	FUSC family protein	-
ACOCI8_RS06485 (ACOCI8_06485)	map	1311261..1312019 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACOCI8_RS06490 (ACOCI8_06490)	-	1312236..1312622 (+)	387	WP_096002295.1	hypothetical protein	-
ACOCI8_RS06495 (ACOCI8_06495)	liaF	1312637..1313338 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACOCI8_RS06500 (ACOCI8_06500)	vraS	1313335..1314378 (+)	1044	WP_096777928.1	sensor histidine kinase	Regulator
ACOCI8_RS06505 (ACOCI8_06505)	vraR	1314368..1314997 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACOCI8_RS06510 (ACOCI8_06510)	-	1315110..1316327 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACOCI8_RS06515 (ACOCI8_06515)	-	1316605..1316880 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACOCI8_RS06520 (ACOCI8_06520)	-	1316887..1317351 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACOCI8_RS06525 (ACOCI8_06525)	-	1317498..1317698 (+)	201	WP_000180460.1	DUF1128 family protein	-
ACOCI8_RS06530 (ACOCI8_06530)	-	1317701..1318957 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40062.55 Da
• Isoelectric Point: 6.0577

>NTDB_id=1109574 ACOCI8_RS06500 WP_096777928.1 1313335..1314378(+) (vraS) [Staphylococcus aureus strain SCTW2018065]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILMCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1109574 ACOCI8_RS06500 WP_096777928.1 1313335..1314378(+) (vraS) [Staphylococcus aureus strain SCTW2018065]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTAATGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997