Detailed information NTG1109568

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCI8_RS02615
• Genome accession: NZ_CP184563
• Coordinates: 575450..576337 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2018065
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 570450..581337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCI8_RS02585 (ACOCI8_02585)	-	571183..571944 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCI8_RS02590 (ACOCI8_02590)	-	572188..572643 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCI8_RS02595 (ACOCI8_02595)	-	572765..572866 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCI8_RS02600 (ACOCI8_02600)	-	572926..574350 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCI8_RS02605 (ACOCI8_02605)	-	574548..574748 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCI8_RS02610 (ACOCI8_02610)	braR	574774..575439 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCI8_RS02615 (ACOCI8_02615)	braS	575450..576337 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCI8_RS02620 (ACOCI8_02620)	-	576445..577200 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCI8_RS02625 (ACOCI8_02625)	-	577197..579197 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCI8_RS02630 (ACOCI8_02630)	-	579866..579979 (+)	114	WP_014937089.1	hypothetical protein	-
ACOCI8_RS02635 (ACOCI8_02635)	-	580361..580621 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCI8_RS02640 (ACOCI8_02640)	-	580631..581128 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCI8_RS02645 (ACOCI8_02645)	-	581236..581328 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109568 ACOCI8_RS02615 WP_000143420.1 575450..576337(+) (braS) [Staphylococcus aureus strain SCTW2018065]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109568 ACOCI8_RS02615 WP_000143420.1 575450..576337(+) (braS) [Staphylococcus aureus strain SCTW2018065]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993