Detailed information NTG1109562

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJJ_RS13765
• Genome accession: NZ_CP184561
• Coordinates: 2725918..2726805 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CBTW2018311
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2720918..2731805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJJ_RS13735 (ACOCJJ_13735)	-	2720927..2721019 (+)	93	WP_031774855.1	hypothetical protein	-
ACOCJJ_RS13740 (ACOCJJ_13740)	-	2721127..2721624 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJJ_RS13745 (ACOCJJ_13745)	-	2721634..2721894 (-)	261	WP_014937088.1	hypothetical protein	-
ACOCJJ_RS13750 (ACOCJJ_13750)	-	2722276..2722389 (-)	114	WP_014937089.1	hypothetical protein	-
ACOCJJ_RS13755 (ACOCJJ_13755)	-	2723058..2725058 (-)	2001	WP_103203960.1	ABC transporter permease	-
ACOCJJ_RS13760 (ACOCJJ_13760)	-	2725055..2725810 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJJ_RS13765 (ACOCJJ_13765)	braS	2725918..2726805 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJJ_RS13770 (ACOCJJ_13770)	braR	2726816..2727481 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJJ_RS13775 (ACOCJJ_13775)	-	2727507..2727707 (-)	201	WP_000604731.1	hypothetical protein	-
ACOCJJ_RS13780 (ACOCJJ_13780)	-	2727905..2729329 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJJ_RS13785 (ACOCJJ_13785)	-	2729389..2729490 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJJ_RS13790 (ACOCJJ_13790)	-	2729612..2730067 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJJ_RS13795 (ACOCJJ_13795)	-	2730311..2731072 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109562 ACOCJJ_RS13765 WP_000143420.1 2725918..2726805(-) (braS) [Staphylococcus aureus strain CBTW2018311]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109562 ACOCJJ_RS13765 WP_000143420.1 2725918..2726805(-) (braS) [Staphylococcus aureus strain CBTW2018311]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993