Detailed information NTG1109517

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJH_RS13760
• Genome accession: NZ_CP184559
• Coordinates: 2727173..2728060 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CBTW2018367
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2722173..2733060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJH_RS13730 (ACOCJH_13730)	-	2722182..2722274 (+)	93	WP_031774855.1	hypothetical protein	-
ACOCJH_RS13735 (ACOCJH_13735)	-	2722382..2722879 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJH_RS13740 (ACOCJH_13740)	-	2722889..2723149 (-)	261	WP_014937088.1	hypothetical protein	-
ACOCJH_RS13745 (ACOCJH_13745)	-	2723531..2723644 (-)	114	WP_014937089.1	hypothetical protein	-
ACOCJH_RS13750 (ACOCJH_13750)	-	2724313..2726313 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJH_RS13755 (ACOCJH_13755)	-	2726310..2727065 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJH_RS13760 (ACOCJH_13760)	braS	2727173..2728060 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJH_RS13765 (ACOCJH_13765)	braR	2728071..2728736 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJH_RS13770 (ACOCJH_13770)	-	2728762..2728962 (-)	201	WP_000604731.1	hypothetical protein	-
ACOCJH_RS13775 (ACOCJH_13775)	-	2729160..2730584 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJH_RS13780 (ACOCJH_13780)	-	2730644..2730745 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJH_RS13785 (ACOCJH_13785)	-	2730867..2731322 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJH_RS13790 (ACOCJH_13790)	-	2731566..2732327 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109517 ACOCJH_RS13760 WP_000143420.1 2727173..2728060(-) (braS) [Staphylococcus aureus strain CBTW2018367]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109517 ACOCJH_RS13760 WP_000143420.1 2727173..2728060(-) (braS) [Staphylococcus aureus strain CBTW2018367]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993