Detailed information NTG1109342

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJI_RS02370
• Genome accession: NZ_CP184551
• Coordinates: 459605..460492 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2019099
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 454605..465492

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJI_RS02340 (ACOCJI_02340)	-	454614..454706 (+)	93	WP_031774855.1	hypothetical protein	-
ACOCJI_RS02345 (ACOCJI_02345)	-	454814..455311 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJI_RS02350 (ACOCJI_02350)	-	455321..455581 (-)	261	WP_014937088.1	hypothetical protein	-
ACOCJI_RS02355 (ACOCJI_02355)	-	455963..456076 (-)	114	WP_084578737.1	hypothetical protein	-
ACOCJI_RS02360 (ACOCJI_02360)	-	456745..458745 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJI_RS02365 (ACOCJI_02365)	-	458742..459497 (-)	756	WP_420228594.1	ABC transporter ATP-binding protein	-
ACOCJI_RS02370 (ACOCJI_02370)	braS	459605..460492 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJI_RS02375 (ACOCJI_02375)	braR	460503..461168 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJI_RS02380 (ACOCJI_02380)	-	461194..461394 (-)	201	WP_000604731.1	hypothetical protein	-
ACOCJI_RS02385 (ACOCJI_02385)	-	461592..463016 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJI_RS02390 (ACOCJI_02390)	-	463076..463177 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJI_RS02395 (ACOCJI_02395)	-	463299..463754 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJI_RS02400 (ACOCJI_02400)	-	463998..464759 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109342 ACOCJI_RS02370 WP_000143420.1 459605..460492(-) (braS) [Staphylococcus aureus strain SCTW2019099]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109342 ACOCJI_RS02370 WP_000143420.1 459605..460492(-) (braS) [Staphylococcus aureus strain SCTW2019099]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993