Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACOCJC_RS06105 Genome accession   NZ_CP184549
Coordinates   1261767..1262483 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain SCTW2019145     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1256767..1267483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACOCJC_RS06090 (ACOCJC_06090) - 1257854..1258804 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  ACOCJC_RS06095 (ACOCJC_06095) - 1258953..1260437 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACOCJC_RS06100 (ACOCJC_06100) - 1260434..1261393 (+) 960 WP_084578717.1 carbohydrate kinase family protein -
  ACOCJC_RS06105 (ACOCJC_06105) agrA 1261767..1262483 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACOCJC_RS06110 (ACOCJC_06110) agrC 1262502..1263794 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  ACOCJC_RS06115 (ACOCJC_06115) agrD 1263819..1263959 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACOCJC_RS06120 (ACOCJC_06120) agrB 1263956..1264525 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACOCJC_RS06125 (ACOCJC_06125) hld 1264815..1264895 (+) 81 WP_000046022.1 delta-hemolysin -
  ACOCJC_RS06130 (ACOCJC_06130) - 1265497..1266282 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  ACOCJC_RS06135 (ACOCJC_06135) - 1266590..1267216 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1109306 ACOCJC_RS06105 WP_000688492.1 1261767..1262483(-) (agrA) [Staphylococcus aureus strain SCTW2019145]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1109306 ACOCJC_RS06105 WP_000688492.1 1261767..1262483(-) (agrA) [Staphylococcus aureus strain SCTW2019145]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment