Detailed information NTG1109302

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJC_RS02970
• Genome accession: NZ_CP184549
• Coordinates: 645340..646227 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2019145
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 640340..651227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJC_RS02940 (ACOCJC_02940)	-	641084..641833 (+)	750	WP_420228373.1	alpha/beta hydrolase	-
ACOCJC_RS02945 (ACOCJC_02945)	-	642078..642533 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJC_RS02950 (ACOCJC_02950)	-	642655..642756 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJC_RS02955 (ACOCJC_02955)	-	642816..644240 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJC_RS02960 (ACOCJC_02960)	-	644438..644638 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJC_RS02965 (ACOCJC_02965)	braR	644664..645329 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJC_RS02970 (ACOCJC_02970)	braS	645340..646227 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJC_RS02975 (ACOCJC_02975)	-	646335..647090 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJC_RS02980 (ACOCJC_02980)	-	647087..649087 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJC_RS02985 (ACOCJC_02985)	-	649756..649869 (+)	114	WP_084578737.1	hypothetical protein	-
ACOCJC_RS02990 (ACOCJC_02990)	-	650251..650511 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJC_RS02995 (ACOCJC_02995)	-	650521..651018 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJC_RS03000 (ACOCJC_03000)	-	651126..651218 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109302 ACOCJC_RS02970 WP_000143420.1 645340..646227(+) (braS) [Staphylococcus aureus strain SCTW2019145]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109302 ACOCJC_RS02970 WP_000143420.1 645340..646227(+) (braS) [Staphylococcus aureus strain SCTW2019145]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993