Detailed information NTG1109292

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJE_RS10075
• Genome accession: NZ_CP184547
• Coordinates: 2081128..2082015 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2021015
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2076128..2087015

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJE_RS10045 (ACOCJE_10045)	-	2076861..2077622 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCJE_RS10050 (ACOCJE_10050)	-	2077866..2078321 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJE_RS10055 (ACOCJE_10055)	-	2078443..2078544 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJE_RS10060 (ACOCJE_10060)	-	2078604..2080028 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJE_RS10065 (ACOCJE_10065)	-	2080226..2080426 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJE_RS10070 (ACOCJE_10070)	braR	2080452..2081117 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJE_RS10075 (ACOCJE_10075)	braS	2081128..2082015 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJE_RS10080 (ACOCJE_10080)	-	2082123..2082878 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJE_RS10085 (ACOCJE_10085)	-	2082875..2084875 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJE_RS10090 (ACOCJE_10090)	-	2085544..2085657 (+)	114	WP_084578737.1	hypothetical protein	-
ACOCJE_RS10095 (ACOCJE_10095)	-	2086039..2086299 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJE_RS10100 (ACOCJE_10100)	-	2086309..2086806 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJE_RS10105 (ACOCJE_10105)	-	2086914..2087006 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109292 ACOCJE_RS10075 WP_000143420.1 2081128..2082015(+) (braS) [Staphylococcus aureus strain SCTW2021015]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109292 ACOCJE_RS10075 WP_000143420.1 2081128..2082015(+) (braS) [Staphylococcus aureus strain SCTW2021015]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993