Detailed information NTG1109248

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJG_RS10500
• Genome accession: NZ_CP184545
• Coordinates: 2152950..2153837 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CBTW2022135
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2147950..2158837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJG_RS10470 (ACOCJG_10470)	-	2148683..2149444 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCJG_RS10475 (ACOCJG_10475)	-	2149688..2150143 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJG_RS10480 (ACOCJG_10480)	-	2150265..2150366 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJG_RS10485 (ACOCJG_10485)	-	2150426..2151850 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJG_RS10490 (ACOCJG_10490)	-	2152048..2152248 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJG_RS10495 (ACOCJG_10495)	braR	2152274..2152939 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJG_RS10500 (ACOCJG_10500)	braS	2152950..2153837 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJG_RS10505 (ACOCJG_10505)	-	2153945..2154700 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJG_RS10510 (ACOCJG_10510)	-	2154697..2156697 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJG_RS10515 (ACOCJG_10515)	-	2157366..2157479 (+)	114	WP_014937089.1	hypothetical protein	-
ACOCJG_RS10520 (ACOCJG_10520)	-	2157861..2158121 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJG_RS10525 (ACOCJG_10525)	-	2158131..2158628 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJG_RS10530 (ACOCJG_10530)	-	2158736..2158828 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109248 ACOCJG_RS10500 WP_000143420.1 2152950..2153837(+) (braS) [Staphylococcus aureus strain CBTW2022135]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109248 ACOCJG_RS10500 WP_000143420.1 2152950..2153837(+) (braS) [Staphylococcus aureus strain CBTW2022135]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993