Detailed information NTG1109163

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJK_RS13420
• Genome accession: NZ_CP184541
• Coordinates: 2689000..2689887 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2022336
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2684000..2694887

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJK_RS13390 (ACOCJK_13390)	-	2684009..2684101 (+)	93	WP_031774855.1	hypothetical protein	-
ACOCJK_RS13395 (ACOCJK_13395)	-	2684209..2684706 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJK_RS13400 (ACOCJK_13400)	-	2684716..2684976 (-)	261	WP_014937088.1	hypothetical protein	-
ACOCJK_RS13405 (ACOCJK_13405)	-	2685358..2685471 (-)	114	WP_014937089.1	hypothetical protein	-
ACOCJK_RS13410 (ACOCJK_13410)	-	2686140..2688140 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJK_RS13415 (ACOCJK_13415)	-	2688137..2688892 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJK_RS13420 (ACOCJK_13420)	braS	2689000..2689887 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJK_RS13425 (ACOCJK_13425)	braR	2689898..2690563 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJK_RS13430 (ACOCJK_13430)	-	2690589..2690789 (-)	201	WP_000604731.1	hypothetical protein	-
ACOCJK_RS13435 (ACOCJK_13435)	-	2690987..2692411 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJK_RS13440 (ACOCJK_13440)	-	2692471..2692572 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJK_RS13445 (ACOCJK_13445)	-	2692694..2693149 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJK_RS13450 (ACOCJK_13450)	-	2693393..2694154 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109163 ACOCJK_RS13420 WP_000143420.1 2689000..2689887(-) (braS) [Staphylococcus aureus strain SCTW2022336]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109163 ACOCJK_RS13420 WP_000143420.1 2689000..2689887(-) (braS) [Staphylococcus aureus strain SCTW2022336]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993