Detailed information NTG0110893

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ID09_RS09870
• Genome accession: NZ_CP008921
• Coordinates: 2018746..2021199 (-)
• Length: 817 a.a.
• NCBI ID: WP_002937803.1
• Uniprot ID: -
• Organism: Streptococcus suis 6407
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2013746..2026199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ID09_RS09840 (ID09_10100)	hslO	2015087..2015953 (+)	867	WP_024381112.1	Hsp33 family molecular chaperone HslO	-
ID09_RS09845 (ID09_10105)	dusB	2015946..2016950 (+)	1005	WP_002937787.1	tRNA dihydrouridine synthase DusB	-
ID09_RS09850 (ID09_10110)	-	2017064..2017306 (-)	243	WP_002937789.1	hypothetical protein	-
ID09_RS09855 (ID09_10115)	-	2017303..2017536 (-)	234	WP_002937793.1	hypothetical protein	-
ID09_RS09860 (ID09_10120)	-	2017556..2017939 (-)	384	WP_002937798.1	hypothetical protein	-
ID09_RS09865 (ID09_10125)	-	2018136..2018627 (-)	492	WP_002937801.1	adenylyltransferase/cytidyltransferase family protein	-
ID09_RS09870 (ID09_10130)	clpC	2018746..2021199 (-)	2454	WP_002937803.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ID09_RS09875 (ID09_10135)	-	2021203..2021661 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
ID09_RS09880 (ID09_10140)	-	2021931..2022269 (+)	339	WP_002937812.1	thioredoxin domain-containing protein	-
ID09_RS09885 (ID09_10145)	-	2022269..2022970 (+)	702	WP_024381113.1	hypothetical protein	-
ID09_RS09890 (ID09_10150)	tsf	2023124..2024164 (-)	1041	WP_014736447.1	translation elongation factor Ts	-
ID09_RS09895 (ID09_10155)	rpsB	2024318..2025094 (-)	777	WP_024381114.1	30S ribosomal protein S2	-
ID09_RS09900 (ID09_10160)	-	2025441..2025953 (-)	513	WP_013730593.1	adenylate kinase	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90368.85 Da
• Isoelectric Point: 6.0792

>NTDB_id=110893 ID09_RS09870 WP_002937803.1 2018746..2021199(-) (clpC) [Streptococcus suis 6407]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFIVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNVEARAGFTKEDLK
AIRSVMKGGKAKPANMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTESDMQDVVKVMVKPLFAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=110893 ID09_RS09870 WP_002937803.1 2018746..2021199(-) (clpC) [Streptococcus suis 6407]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGCTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTATTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACGTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTGCCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ATGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCAACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTACCGGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTGTCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAGGCCTACCGTCCTGAATTTATCAACCGTATTGATGAAAAAGTTGTCTTC
CATAGTTTGACCGAATCCGATATGCAGGATGTTGTCAAGGTCATGGTCAAACCGTTGTTTGCGGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTACGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGTTCGACC
CTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (372-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.779	99.755	0.716
clpC	Streptococcus pneumoniae D39	71.779	99.755	0.716
clpC	Streptococcus pneumoniae TIGR4	71.779	99.755	0.716
clpC	Streptococcus mutans UA159	67.076	99.633	0.668
clpC	Streptococcus thermophilus LMD-9	64.081	100	0.657
clpC	Streptococcus thermophilus LMG 18311	64.501	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.281	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.114	100	0.441