Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ID09_RS02065 Genome accession   NZ_CP008921
Coordinates   411123..411764 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis 6407     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 406123..416764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS02045 (ID09_02070) - 406291..407028 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ID09_RS02050 (ID09_02075) pknB 407028..408680 (+) 1653 Protein_364 Stk1 family PASTA domain-containing Ser/Thr kinase -
  ID09_RS12625 - 408807..409022 (+) 216 Protein_365 serine/threonine protein kinase -
  ID09_RS02055 (ID09_02080) liaF 409443..410138 (+) 696 WP_024381715.1 cell wall-active antibiotics response protein LiaF -
  ID09_RS02060 (ID09_02085) - 410135..411151 (+) 1017 WP_002937028.1 sensor histidine kinase -
  ID09_RS02065 (ID09_02090) vraR 411123..411764 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  ID09_RS02070 (ID09_02095) - 411814..413214 (+) 1401 WP_024381714.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ID09_RS02075 (ID09_02100) - 413216..413587 (+) 372 WP_024381713.1 S1 RNA-binding domain-containing protein -
  ID09_RS02080 (ID09_02105) cysK 413613..414539 (-) 927 WP_002937015.1 cysteine synthase A -
  ID09_RS02085 (ID09_02110) - 414628..415260 (-) 633 WP_023369489.1 YigZ family protein -
  ID09_RS02090 (ID09_02115) comFA/cflA 415317..416609 (+) 1293 WP_024390587.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=110836 ID09_RS02065 WP_002937025.1 411123..411764(+) (vraR) [Streptococcus suis 6407]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=110836 ID09_RS02065 WP_002937025.1 411123..411764(+) (vraR) [Streptococcus suis 6407]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAGGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment