Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM595_RS05255 Genome accession   NZ_CP183796
Coordinates   1051605..1052321 (+) Length   238 a.a.
NCBI ID   WP_002482781.1    Uniprot ID   A0A380HJP0
Organism   Staphylococcus sp. LKG3-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1046605..1057321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM595_RS05230 (ACM595_05230) - 1047193..1047822 (+) 630 WP_069821659.1 nitroreductase family protein -
  ACM595_RS05235 (ACM595_05235) - 1047993..1048778 (+) 786 WP_011302730.1 carbon-nitrogen family hydrolase -
  ACM595_RS05240 (ACM595_05240) - 1049538..1050107 (+) 570 WP_075340051.1 accessory gene regulator AgrB -
  ACM595_RS05245 (ACM595_05245) agrD 1050110..1050271 (+) 162 WP_002482783.1 cyclic lactone autoinducer peptide AgrD -
  ACM595_RS05250 (ACM595_05250) agrC 1050297..1051592 (+) 1296 WP_115347306.1 quorum-sensing sensor histidine kinase AgrC -
  ACM595_RS05255 (ACM595_05255) agrA 1051605..1052321 (+) 717 WP_002482781.1 quorum-sensing response regulator AgrA Regulator
  ACM595_RS05260 (ACM595_05260) - 1052398..1053366 (-) 969 WP_206260867.1 carbohydrate kinase family protein -
  ACM595_RS05265 (ACM595_05265) - 1053363..1054847 (-) 1485 WP_011302726.1 sucrose-6-phosphate hydrolase -
  ACM595_RS05270 (ACM595_05270) - 1054933..1055886 (-) 954 WP_206260871.1 LacI family DNA-binding transcriptional regulator -
  ACM595_RS05275 (ACM595_05275) - 1056032..1056256 (-) 225 WP_002482777.1 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27954.74 Da        Isoelectric Point: 5.0875

>NTDB_id=1106121 ACM595_RS05255 WP_002482781.1 1051605..1052321(+) (agrA) [Staphylococcus sp. LKG3-1]
MKIFICEDDERQREHMVSIINNYIMIEEKPMEIEVATADPYDILERSKNLNDIGCYFLDIQLEADINGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRIIDCLETSESRLKLLSKESSVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELDQLDERFFRCHNSFVVNRHNIDSIDSKSRVVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1106121 ACM595_RS05255 WP_002482781.1 1051605..1052321(+) (agrA) [Staphylococcus sp. LKG3-1]
GTGAAAATATTCATTTGTGAAGATGATGAAAGACAACGTGAGCACATGGTTTCTATTATTAATAACTACATCATGATTGA
AGAAAAGCCAATGGAAATCGAAGTTGCCACTGCTGATCCTTATGACATCTTAGAACGCTCTAAGAACCTCAATGATATTG
GGTGTTATTTTTTAGATATTCAGCTTGAAGCTGATATTAATGGTATCAAACTTGCTAGTGAGATTCGTAAACATGATCCT
GTAGGTAATATCATCTTTGTTACAAGTCACAGTGAGTTAACTTACCTAACATTTGTCTATAAGGTAGCCGCGATGGATTT
CATTTTTAAAGATGATCCAGATGAATTAAAATCAAGAATTATTGACTGTCTTGAAACTTCAGAATCAAGATTGAAGCTTC
TTTCAAAAGAAAGTAGTGTTGAAACAATTGAATTAAAACGTGGAAGTAATTCGATTTATGTCCAATATGATGATGTTATG
TTCTTTGAATCATCTACTAAATCGCATCGATTGATTGCACATCTTGATAATCGTCAAATTGAGTTTTATGGCAATTTAAA
AGAATTAGATCAACTTGATGAGCGATTTTTCAGATGTCATAATAGCTTTGTCGTCAATAGACACAATATAGATTCTATTG
ACTCTAAGTCACGTGTTGTCTATTTTAAAAATAATGAACATTGCTATGCATCTGTTAGAAATGTCAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

85.714

100

0.857

Multiple sequence alignment