Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM592_RS05570 Genome accession   NZ_CP183792
Coordinates   1246298..1247014 (-) Length   238 a.a.
NCBI ID   WP_029378924.1    Uniprot ID   A0A418I5B6
Organism   Staphylococcus sp. Ze3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241298..1252014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM592_RS05550 (ACM592_05550) - 1241963..1242187 (+) 225 WP_042362355.1 sulfurtransferase TusA family protein -
  ACM592_RS05555 (ACM592_05555) - 1242769..1243731 (+) 963 WP_029378921.1 LacI family DNA-binding transcriptional regulator -
  ACM592_RS05560 (ACM592_05560) - 1243816..1245300 (+) 1485 WP_081225102.1 sucrose-6-phosphate hydrolase -
  ACM592_RS05565 (ACM592_05565) - 1245297..1246262 (+) 966 WP_225489537.1 carbohydrate kinase family protein -
  ACM592_RS05570 (ACM592_05570) agrA 1246298..1247014 (-) 717 WP_029378924.1 quorum-sensing response regulator AgrA Regulator
  ACM592_RS05575 (ACM592_05575) agrC 1247027..1248322 (-) 1296 WP_326026908.1 quorum-sensing sensor histidine kinase AgrC -
  ACM592_RS05580 (ACM592_05580) agrD 1248352..1248489 (-) 138 WP_069795725.1 cyclic lactone autoinducer peptide AgrD -
  ACM592_RS05585 (ACM592_05585) - 1248492..1249061 (-) 570 WP_326026907.1 accessory gene regulator AgrB -
  ACM592_RS05590 (ACM592_05590) - 1249828..1250613 (-) 786 WP_047172118.1 carbon-nitrogen family hydrolase -
  ACM592_RS05595 (ACM592_05595) - 1250977..1251606 (-) 630 WP_042362363.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27939.77 Da        Isoelectric Point: 5.4095

>NTDB_id=1106076 ACM592_RS05570 WP_029378924.1 1246298..1247014(-) (agrA) [Staphylococcus sp. Ze3]
MKIFICEDDERQREHMVSIINNYIMIEEKPMEIEVATADPYDILERSKNINDIGCYFLDIQLEADINGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRVIDCLETSESRLKLLSKESSVETIELKRGSNSIYVQYDDVM
FFESSSKSHRLIAHLDNRQIEFYGNLKEIDQLDKRFFRCHNSFVVNRHNIESIDSKSRVVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1106076 ACM592_RS05570 WP_029378924.1 1246298..1247014(-) (agrA) [Staphylococcus sp. Ze3]
GTGAAAATATTCATTTGTGAAGATGATGAAAGACAACGTGAACATATGGTTTCAATTATAAATAACTATATTATGATTGA
AGAAAAACCAATGGAAATTGAAGTTGCGACAGCTGATCCTTATGACATTTTAGAACGCTCAAAGAACATTAATGATATAG
GATGTTACTTTTTAGATATTCAACTAGAAGCTGACATCAACGGAATCAAGCTTGCAAGTGAAATACGTAAACATGATCCG
GTTGGCAATATCATTTTTGTTACAAGTCATAGTGAACTGACATACTTAACATTTGTCTACAAGGTTGCAGCAATGGATTT
CATTTTCAAAGATGATCCAGACGAATTAAAATCAAGAGTGATTGATTGCTTAGAAACATCTGAGTCACGACTAAAACTAC
TTTCAAAAGAAAGCAGCGTCGAAACAATAGAATTAAAACGTGGTAGCAATTCTATTTATGTACAATATGACGATGTGATG
TTCTTCGAATCATCTAGTAAATCCCATCGCTTAATCGCACATCTCGATAATCGTCAAATCGAATTTTATGGAAACCTTAA
AGAAATTGATCAGTTAGATAAACGCTTCTTTAGATGTCATAATAGTTTTGTAGTAAATAGACACAATATTGAGTCCATCG
ACTCTAAATCACGTGTAGTTTATTTTAAAAACAATGAACATTGTTATGCTTCTGTAAGAAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A418I5B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

84.874

100

0.849

Multiple sequence alignment