Detailed information NTG1105981

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V3C22_RS09150
• Genome accession: NZ_CP183775
• Coordinates: 1851478..1853919 (-)
• Length: 813 a.a.
• NCBI ID: WP_226708921.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain Xc
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1846478..1858919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V3C22_RS09135 (V3C22_09135)	rpsJ	1847300..1847608 (-)	309	WP_002262341.1	30S ribosomal protein S10	-
V3C22_RS09140 (V3C22_09140)	-	1847928..1848614 (+)	687	WP_002266894.1	helix-turn-helix domain-containing protein	-
V3C22_RS09145 (V3C22_09145)	-	1848804..1851191 (-)	2388	WP_226707365.1	glycoside hydrolase family 68 protein	-
V3C22_RS09150 (V3C22_09150)	clpC	1851478..1853919 (-)	2442	WP_226708921.1	AAA family ATPase	Regulator
V3C22_RS09155 (V3C22_09155)	ctsR	1853916..1854380 (-)	465	WP_002262345.1	transcriptional regulator CtsR	-
V3C22_RS09160 (V3C22_09160)	tsf	1854665..1855711 (-)	1047	WP_002306469.1	translation elongation factor Ts	-
V3C22_RS09165 (V3C22_09165)	rpsB	1855771..1856562 (-)	792	WP_019314231.1	30S ribosomal protein S2	-
V3C22_RS09170 (V3C22_09170)	-	1856750..1858603 (-)	1854	WP_002268007.1	hypothetical protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90305.13 Da
• Isoelectric Point: 6.8004

>NTDB_id=1105981 V3C22_RS09150 WP_226708921.1 1851478..1853919(-) (clpC) [Streptococcus mutans strain Xc]
MTDYSLKMQEVFRLAQFEAARFESSYLESWHVLLAMVEIDSSVAGLSFAEFEADVRFEDYQAAAILAIGKKPKSSSNDIM
LLEQSHALKRTLAEAAAISQVTHAKEVGTEHVLFAMLLNPNLLATRILELVGFHAKDDGESIRLLDLRKVIERYAGFSKE
DIKTIFEMRKPKKVKNSSSFSDLMKPPSVTGELADFTRDLTELARQGRLEPVIGREQEISRMVQILSRKTKNNPVLVGDA
GVGKTALAYGLAQRIVDSAVPFELADMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIVLFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTIGATTQEEYQKHIEKDAALSRRFAKVTIEEPSEEEAYQILLGLKKSYETYHHVIISDA
AVMAAVKGAHRYLSGKNLPDSAIDLLDEASATVQGLVKKKAPAYLTDLDHALIINDYQLAKCLLKKEKKPLLKKRAEVKE
EDILATLSKLSGIPVKKLTQADSKKYLNLERELHKRVIGQDDAVSSISRAIRRNQSGIRVGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKSFSQDYKAMESRILEELKKVYRPEFINRIDEKVVFHN
LGQEDIRHVVKIMVAPLIAHLADQGITLKFQPSALKHLALAGYDAEMGARPLRRTLQTEVEDKLAELILSGKLASGQTLK
IGIQKEKLKFDIV

Nucleotide

• Length: 2442 bp

>NTDB_id=1105981 V3C22_RS09150 WP_226708921.1 1851478..1853919(-) (clpC) [Streptococcus mutans strain Xc]
ATGACCGATTACTCATTAAAAATGCAGGAAGTCTTTCGATTGGCGCAGTTTGAAGCAGCTCGTTTTGAAAGTTCCTATTT
AGAAAGCTGGCATGTCCTTCTTGCAATGGTAGAGATTGATTCCTCAGTGGCTGGTTTAAGTTTTGCGGAGTTTGAAGCAG
ATGTCCGTTTTGAGGATTATCAGGCTGCTGCTATTTTGGCGATTGGTAAAAAGCCTAAGTCCTCGAGTAATGATATTATG
CTTTTAGAGCAATCACATGCTTTAAAACGAACCCTAGCAGAGGCCGCTGCTATTAGTCAGGTGACACACGCTAAAGAAGT
CGGCACAGAACATGTTCTCTTTGCTATGTTACTGAATCCTAATCTTTTGGCGACTCGCATTTTAGAATTAGTTGGTTTTC
ACGCCAAAGATGATGGAGAGTCTATCCGTCTTTTGGATCTGCGAAAAGTGATTGAACGTTATGCTGGCTTTTCCAAAGAG
GACATTAAGACCATCTTTGAAATGCGTAAACCTAAAAAGGTCAAAAATAGCAGCAGCTTTTCTGATTTAATGAAGCCACC
TAGCGTTACAGGTGAACTAGCTGATTTTACACGGGATTTGACGGAGTTGGCAAGACAAGGTCGTTTAGAACCTGTTATTG
GCCGTGAACAAGAAATTTCACGGATGGTTCAAATTTTAAGCCGTAAGACAAAAAATAATCCTGTTTTAGTTGGCGATGCT
GGTGTTGGGAAGACGGCCTTGGCTTACGGCCTTGCTCAACGTATTGTGGATAGTGCCGTTCCTTTTGAATTGGCAGATAT
GAAAGTACTAGAGCTCGATATGATGAGTGTTGTTGCAGGAACTCGTTTTCGTGGCGATTTTGAGGAACGAATGAATCAAA
TTATTGCAGACATTGAAGCTGATGGTCACATTGTCCTCTTCATTGATGAGCTGCATACCATTATGGGTTCAGGAAGTGGT
ATTGATAGTACGCTGGATGCTGCTAATATTCTTAAACCAGCTTTAGCGCGCGGGAGTCTTAGAACGATTGGAGCGACTAC
TCAAGAGGAGTATCAAAAGCATATTGAAAAAGATGCTGCTCTTTCTCGCCGTTTTGCTAAGGTAACTATTGAAGAACCAA
GTGAAGAAGAAGCTTATCAGATCTTGCTTGGTTTAAAGAAAAGTTATGAAACTTATCATCATGTTATTATTTCTGATGCA
GCCGTAATGGCGGCAGTCAAAGGAGCACATCGTTATTTAAGTGGTAAAAATTTACCTGATTCGGCTATCGATCTTTTAGA
TGAAGCTAGTGCAACTGTTCAAGGCTTAGTGAAAAAAAAGGCACCAGCTTATTTGACGGATTTAGATCACGCTCTTATCA
TTAACGATTACCAATTAGCTAAGTGTTTGCTGAAAAAGGAGAAGAAGCCTCTGCTTAAAAAACGAGCTGAAGTCAAGGAA
GAAGATATCCTAGCTACTCTCAGCAAACTTTCGGGCATCCCTGTCAAAAAATTAACACAGGCTGACAGTAAAAAGTACCT
TAATCTCGAAAGGGAATTACATAAGCGTGTAATTGGTCAAGACGATGCGGTGTCCAGTATCAGCCGTGCTATTCGCCGCA
ATCAATCCGGAATTCGGGTTGGCAAACGTCCCATTGGTTCTTTCATGTTTTTGGGGCCGACAGGTGTTGGTAAAACAGAG
CTTGCTAAGGCTTTGGCAGAAGTGCTTTTTGATGATGAGTCAGCTCTTATTCGTTTTGACATGAGCGAATATATGGAAAA
ATTTGCAGCTTCTCGCCTTAATGGAGCTCCTCCGGGCTATGTGGGGTATGAAGAAGGCGGTGAGTTGACGGAAAAGGTTC
GTAACAAACCTTACTCTGTTCTTCTTTTTGATGAGGTGGAAAAAGCTCATCCAGATATTTTCAATATCTTACTTCAAGTA
CTTGATGATGGTGTTTTGACAGATAGCCGTGGTCGCAAAGTTGATTTTTCAAATACGATTATTATCATGACCTCTAATTT
GGGTGCGACTGCGCTTCGTGATGATAAAACCGTTGGTTTTGGAGCTAAAAGCTTTTCTCAGGATTATAAGGCCATGGAAA
GTCGTATTTTAGAGGAATTAAAAAAGGTTTACCGACCTGAATTTATTAATCGTATTGATGAAAAAGTTGTCTTTCATAAC
CTTGGTCAAGAAGACATACGCCATGTTGTTAAAATTATGGTTGCTCCATTGATTGCCCATTTGGCTGATCAGGGGATTAC
ACTTAAGTTTCAGCCTTCAGCTTTGAAACATTTAGCTCTGGCAGGTTATGATGCTGAAATGGGGGCACGTCCTTTGCGTC
GGACACTTCAGACAGAAGTGGAAGATAAGTTAGCAGAGCTTATTCTTTCGGGGAAACTAGCCAGTGGACAGACTCTGAAA
ATAGGTATTCAAAAAGAAAAATTAAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (374-452)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-55)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	99.508	100	0.995
clpC	Streptococcus thermophilus LMD-9	72.304	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.181	100	0.724
clpC	Streptococcus pneumoniae TIGR4	66.953	100	0.67
clpC	Streptococcus pneumoniae Rx1	66.953	100	0.67
clpC	Streptococcus pneumoniae D39	66.953	100	0.67
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.86	100	0.501
clpC	Bacillus subtilis subsp. subtilis str. 168	43.894	100	0.446
clpE	Streptococcus pneumoniae TIGR4	47.2	76.876	0.363
clpE	Streptococcus pneumoniae Rx1	47.2	76.876	0.363
clpE	Streptococcus pneumoniae D39	47.2	76.876	0.363
clpE	Streptococcus pneumoniae R6	47.2	76.876	0.363
clpE	Streptococcus mutans UA159	47.04	76.876	0.362