Detailed information NTG1105238

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACNSPI_RS02655
• Genome accession: NZ_CP183317
• Coordinates: 534047..534934 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 529047..539934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNSPI_RS02625 (ACNSPI_02630)	-	529779..530540 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
ACNSPI_RS02630 (ACNSPI_02635)	-	530785..531240 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACNSPI_RS02635 (ACNSPI_02640)	-	531362..531463 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACNSPI_RS02640 (ACNSPI_02645)	-	531523..532947 (-)	1425	WP_000953744.1	alkaline phosphatase	-
ACNSPI_RS02645 (ACNSPI_02650)	-	533145..533345 (+)	201	WP_000604728.1	hypothetical protein	-
ACNSPI_RS02650 (ACNSPI_02655)	braR	533371..534036 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACNSPI_RS02655 (ACNSPI_02660)	braS	534047..534934 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACNSPI_RS02660 (ACNSPI_02665)	-	535042..535797 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACNSPI_RS02665 (ACNSPI_02670)	-	535794..537794 (+)	2001	WP_000776751.1	ABC transporter permease	-
ACNSPI_RS02670 (ACNSPI_02675)	-	538453..538566 (+)	114	WP_001791776.1	hypothetical protein	-
ACNSPI_RS02675 (ACNSPI_02680)	-	538948..539208 (+)	261	WP_001789910.1	hypothetical protein	-
ACNSPI_RS02680 (ACNSPI_02685)	-	539218..539715 (+)	498	WP_001065268.1	glutathione peroxidase	-
ACNSPI_RS02685 (ACNSPI_02690)	-	539823..539915 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1105238 ACNSPI_RS02655 WP_000143419.1 534047..534934(+) (braS) [Staphylococcus aureus strain USA300]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1105238 ACNSPI_RS02655 WP_000143419.1 534047..534934(+) (braS) [Staphylococcus aureus strain USA300]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997