Detailed information NTG0110519

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HV94_RS02410
• Genome accession: NZ_CP008872
• Coordinates: 518032..520830 (+)
• Length: 932 a.a.
• NCBI ID: WP_060774152.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain X78812
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 513032..525830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HV94_RS02380 (HV94_03630)	dbpA	513247..514623 (-)	1377	WP_003113273.1	ATP-dependent RNA helicase DbpA	-
HV94_RS02385 (HV94_03635)	-	514971..515180 (+)	210	WP_003084710.1	cold-shock protein	-
HV94_RS02390 (HV94_03640)	-	515331..515855 (+)	525	WP_003113272.1	ATP-dependent zinc protease	-
HV94_RS02395 (HV94_03645)	-	515849..516223 (-)	375	WP_003142684.1	YkvA family protein	-
HV94_RS02400 (HV94_03650)	mdtD	516225..517658 (-)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
HV94_RS02410 (HV94_03655)	clpC	518032..520830 (+)	2799	WP_060774152.1	AAA family protein disaggregase ClpG	Regulator
HV94_RS02415 (HV94_03660)	-	520932..521510 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
HV94_RS02420 (HV94_03665)	-	521784..522671 (-)	888	WP_003099939.1	acyltransferase	-
HV94_RS02425 (HV94_03670)	-	522814..523323 (+)	510	WP_003084733.1	ATP-dependent zinc protease	-
HV94_RS02430 (HV94_03675)	creB	523408..524097 (+)	690	WP_003113268.1	two-component system response regulator CreB	-
HV94_RS02435 (HV94_03680)	creC	524097..525521 (+)	1425	WP_003113267.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103439.93 Da
• Isoelectric Point: 6.8717

>NTDB_id=110519 HV94_RS02410 WP_060774152.1 518032..520830(+) (clpC) [Pseudomonas aeruginosa strain X78812]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFAAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISRLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPRGRATAARKPAAKKGAAAKGKADKPKTK

Nucleotide

• Length: 2799 bp

>NTDB_id=110519 HV94_RS02410 WP_060774152.1 518032..520830(+) (clpC) [Pseudomonas aeruginosa strain X78812]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCATTACCGCCAGTTGATGCGCCAGCAGCGTATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCGCGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTTCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTTGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGTGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGCCGCCGCCGCCGAGCTGTCCGACCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAGGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCTTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGATGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAATACCATCATCATCGCCACCAGCAACCTAGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGACATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAGTCGCTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCTCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAGCTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAGGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAGTCCGGCGCCGGCGAGACGCCCAGGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGACCAAGTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• AAA lid domain (AAA_lid_9) (427-524)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	86.052	0.433
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.805	88.734	0.38
clpC	Streptococcus thermophilus LMG 18311	42.563	88.734	0.378
clpC	Streptococcus mutans UA159	41.383	88.412	0.366