Detailed information NTG1101806

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: ACNFKJ_RS07365
• Genome accession: NZ_CP182514
• Coordinates: 1430599..1432227 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186602.1
• Uniprot ID: Q9XB94
• Organism: Staphylococcus aureus strain subspecie aureus F-182
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	1412233..1433598	1430599..1432227	within	0

Gene organization within MGE regions

Location: 1412233..1433598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNFKJ_RS07260	mecA	1412233..1414242 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
ACNFKJ_RS07265	mecR1	1414339..1416096 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
ACNFKJ_RS07270	mecI	1416096..1416467 (+)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
ACNFKJ_RS07275	psm-mec	1416552..1416620 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
ACNFKJ_RS07280	-	1416975..1418084 (+)	1110	WP_000943131.1	ROK family transcriptional regulator	-
ACNFKJ_RS07285	cstB	1418198..1419532 (-)	1335	Protein_1399	persulfide dioxygenase-sulfurtransferase CstB	-
ACNFKJ_RS07290	-	1419565..1420629 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
ACNFKJ_RS07295	cstR	1420765..1421025 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
ACNFKJ_RS07300	-	1421025..1421663 (+)	639	Protein_1402	sulfite exporter TauE/SafE family protein	-
ACNFKJ_RS07305	-	1421717..1421776 (-)	60	Protein_1403	DNA repair protein RadC	-
ACNFKJ_RS07310	-	1422008..1422670 (-)	663	WP_001092058.1	class I SAM-dependent methyltransferase	-
ACNFKJ_RS07315	-	1423062..1423121 (+)	60	WP_010959190.1	erythromycin resistance leader peptide	-
ACNFKJ_RS07320	erm(A)	1423204..1423935 (+)	732	WP_001072201.1	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	-
ACNFKJ_RS07325	-	1424061..1424843 (-)	783	WP_000067268.1	aminoglycoside nucleotidyltransferase ANT(9)-Ia	-
ACNFKJ_RS07330	-	1424994..1425371 (-)	378	WP_000361059.1	DUF6262 family protein	-
ACNFKJ_RS07335	-	1425378..1427270 (-)	1893	WP_001557544.1	site-specific integrase	-
ACNFKJ_RS07340	-	1427267..1428352 (-)	1086	WP_000868132.1	tyrosine-type recombinase/integrase	-
ACNFKJ_RS07345	-	1428471..1428788 (-)	318	WP_000659050.1	JAB domain-containing protein	-
ACNFKJ_RS07350	-	1428809..1429315 (-)	507	WP_001092169.1	DUF1643 domain-containing protein	-
ACNFKJ_RS07355	-	1429333..1429644 (-)	312	WP_000700853.1	DUF960 family protein	-
ACNFKJ_RS07360	-	1429731..1430081 (-)	351	WP_000859155.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACNFKJ_RS07365	ccrB	1430599..1432227 (-)	1629	WP_001186602.1	cassette chromosome recombinase CcrB	Machinery gene
ACNFKJ_RS07370	ccrA	1432249..1433598 (-)	1350	WP_000815646.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62664.84 Da
• Isoelectric Point: 9.8600

>NTDB_id=1101806 ACNFKJ_RS07365 WP_001186602.1 1430599..1432227(-) (ccrB) [Staphylococcus aureus strain subspecie aureus F-182]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide

• Length: 1629 bp

>NTDB_id=1101806 ACNFKJ_RS07365 WP_001186602.1 1430599..1432227(-) (ccrB) [Staphylococcus aureus strain subspecie aureus F-182]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

3D structure

• AlphaFold DB: Q9XB94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	100	100	1