Detailed information NTG1101796

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACNFKJ_RS02620
• Genome accession: NZ_CP182514
• Coordinates: 505878..506921 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain subspecie aureus F-182
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 500878..511921

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNFKJ_RS02590	-	501299..502555 (-)	1257	WP_001793983.1	aminopeptidase	-
ACNFKJ_RS02595	-	502558..502758 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACNFKJ_RS02600	-	502905..503369 (+)	465	WP_061843272.1	low molecular weight protein-tyrosine-phosphatase	-
ACNFKJ_RS02605	-	503376..503651 (+)	276	WP_070002542.1	YtxH domain-containing protein	-
ACNFKJ_RS02610	-	503929..505146 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACNFKJ_RS02615	vraR	505259..505888 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACNFKJ_RS02620	vraS	505878..506921 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACNFKJ_RS02625	liaF	506918..507619 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACNFKJ_RS02630	-	507634..508020 (-)	387	WP_001110178.1	hypothetical protein	-
ACNFKJ_RS02635	map	508237..508995 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACNFKJ_RS02640	-	509751..510737 (+)	987	WP_001014423.1	FUSC family protein	-
ACNFKJ_RS02645	-	510865..511320 (-)	456	WP_102695924.1	hypothetical protein	-
ACNFKJ_RS02650	-	511349..511459 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1101796 ACNFKJ_RS02620 WP_001017131.1 505878..506921(-) (vraS) [Staphylococcus aureus strain subspecie aureus F-182]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1101796 ACNFKJ_RS02620 WP_001017131.1 505878..506921(-) (vraS) [Staphylococcus aureus strain subspecie aureus F-182]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1