Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACNI3C_RS12600 Genome accession   NZ_CP182357
Coordinates   2535967..2537805 (+) Length   612 a.a.
NCBI ID   WP_419770160.1    Uniprot ID   -
Organism   MAG: Candidatus Marinarcus sp. isolate PCE-1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2530967..2542805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNI3C_RS12570 (ACNI3C_12570) - 2531204..2531671 (-) 468 WP_419770154.1 hypothetical protein -
  ACNI3C_RS12575 (ACNI3C_12575) ald 2531719..2532801 (-) 1083 WP_419770155.1 alanine dehydrogenase -
  ACNI3C_RS12580 (ACNI3C_12580) - 2532893..2533519 (+) 627 WP_419770156.1 DsbA family protein -
  ACNI3C_RS12585 (ACNI3C_12585) - 2533516..2534403 (-) 888 WP_419770157.1 radical SAM protein -
  ACNI3C_RS12590 (ACNI3C_12590) - 2534516..2534980 (+) 465 WP_419770158.1 J domain-containing protein -
  ACNI3C_RS12595 (ACNI3C_12595) - 2534994..2535632 (-) 639 WP_419770159.1 hypothetical protein -
  ACNI3C_RS12600 (ACNI3C_12600) uvrC 2535967..2537805 (+) 1839 WP_419770160.1 excinuclease ABC subunit UvrC Machinery gene
  ACNI3C_RS12605 (ACNI3C_12605) - 2537821..2538846 (+) 1026 WP_419770161.1 alanine racemase -
  ACNI3C_RS12610 (ACNI3C_12610) - 2538848..2539429 (+) 582 WP_419770162.1 tetratricopeptide repeat protein -
  ACNI3C_RS12615 (ACNI3C_12615) - 2539426..2540181 (-) 756 WP_419770163.1 competence/damage-inducible protein A -
  ACNI3C_RS12620 (ACNI3C_12620) - 2540191..2540760 (-) 570 WP_419770164.1 adenylate kinase -
  ACNI3C_RS12625 (ACNI3C_12625) - 2540863..2542587 (-) 1725 WP_419770165.1 YgiQ family radical SAM protein -

Sequence

Protein


Download         Length: 612 a.a.        Molecular weight: 71036.41 Da        Isoelectric Point: 9.3059

>NTDB_id=1101375 ACNI3C_RS12600 WP_419770160.1 2535967..2537805(+) (uvrC) [MAG: Candidatus Marinarcus sp. isolate PCE-1]
MELSEKLKQLPNESGVYQYFDKEGHLLYVGKAKVLKNRVKSYFKFTPTLAPADKLGLRIYKMITEVASLEWIIVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYIDLSEDFPRLEITRKVLKGSNIKYFGPYSTGARDILDSIYEIVPLVQKKTC
IKGKTACLFHQIKKCHAPCEGKITIQAYKEIVNEALEYIYNKSKLLIKLNEKMQEYSNDFRFEEAMNLRDRIKTIEKSQI
KTGMDLATNENLDLFAIKTNAKKAVVVRMFIRDGKLASSNHNFIKLDFLEDNSEIELDEAYQRAMVNYYTNEIPVLPKEI
LIAQDLEEKENLEAFLTERFSKKIPILNPKVGKKKELMQIALNNCEELLRLESSKNNTTIYEELQKLFQLQRVPARVESF
DNSHMMGQATVGAMVIWEDGFVKSDFRHYNLEALDEYAQMHEMLKRRVESFQTNPAPDLWIIDGGLTLLKLAYNIVESVG
VNIDIIAIAKEKIDAKAHRAKGKAKDILHYKEANGFKELKLSSSDQRLQFVQRQRDEAHRFVIAFHKKQKRKEDKQISLL
QLHGIGEAKVKKLLLYFGTFEEIKRAKVETLKEVLNEKDAIVLFNHFTSNKN

Nucleotide


Download         Length: 1839 bp        

>NTDB_id=1101375 ACNI3C_RS12600 WP_419770160.1 2535967..2537805(+) (uvrC) [MAG: Candidatus Marinarcus sp. isolate PCE-1]
ATGGAATTATCAGAAAAACTCAAACAACTTCCCAATGAATCTGGGGTTTATCAATATTTTGACAAAGAGGGGCATTTGCT
TTATGTAGGCAAAGCAAAAGTTCTTAAAAACAGAGTCAAATCCTATTTTAAATTTACTCCTACTTTAGCTCCTGCTGATA
AATTGGGTTTGAGAATCTATAAAATGATTACAGAAGTGGCCTCTTTAGAGTGGATTATTGTGCCCAATGAACACGATGCC
CTTATTTTAGAGAACTCCTTGATAAAACAACTCAAACCAAAATACAATATTCTCCTACGTGATGACAAAACTTACCCTTA
TATCTATATTGATTTAAGTGAAGATTTTCCCCGACTTGAAATTACCAGAAAGGTGTTAAAAGGTTCAAATATTAAATATT
TTGGTCCCTATTCAACGGGGGCAAGAGACATCTTGGACTCTATTTATGAGATTGTTCCTTTGGTTCAAAAGAAAACCTGC
ATTAAAGGAAAAACTGCGTGTTTATTTCACCAAATAAAAAAGTGTCATGCCCCTTGTGAAGGTAAAATAACCATTCAAGC
GTACAAAGAGATTGTCAATGAAGCCTTAGAGTATATTTATAACAAAAGCAAACTGCTGATCAAACTCAATGAAAAAATGC
AAGAGTATTCTAACGATTTCAGATTTGAAGAGGCAATGAACTTAAGAGATCGAATTAAAACCATTGAAAAATCTCAAATC
AAAACCGGTATGGACTTAGCGACTAATGAAAACCTTGACCTTTTTGCCATTAAAACAAATGCCAAAAAAGCAGTCGTTGT
TCGTATGTTTATTCGAGATGGAAAGCTCGCTTCTTCCAACCATAACTTTATTAAACTGGACTTTTTAGAAGATAACAGCG
AGATAGAACTCGATGAAGCCTACCAAAGAGCCATGGTCAATTACTATACCAATGAAATTCCAGTTTTACCCAAAGAGATT
TTAATTGCACAAGACCTTGAAGAGAAAGAGAATTTAGAAGCATTTTTAACAGAACGGTTTTCTAAAAAAATTCCTATTTT
AAATCCAAAAGTGGGAAAGAAAAAAGAGTTAATGCAAATTGCACTAAATAATTGTGAGGAACTGTTACGACTGGAGAGTT
CAAAAAACAACACTACCATTTATGAAGAGCTGCAAAAACTTTTCCAATTGCAAAGAGTACCTGCCAGAGTTGAGAGTTTC
GACAACTCACATATGATGGGGCAAGCAACGGTTGGTGCGATGGTTATTTGGGAAGACGGTTTTGTAAAATCCGATTTCAG
ACACTACAACTTAGAAGCATTGGATGAGTATGCTCAAATGCATGAGATGTTAAAACGCCGTGTAGAGAGTTTCCAAACCA
ATCCTGCACCCGATTTATGGATAATTGATGGTGGCTTAACGCTTCTAAAATTGGCCTATAATATCGTAGAGTCTGTGGGA
GTCAATATTGATATCATTGCCATAGCCAAAGAGAAAATAGATGCAAAAGCACACCGAGCTAAGGGAAAAGCCAAAGACAT
TCTTCACTATAAAGAGGCGAATGGCTTTAAAGAGTTAAAACTCAGTTCCAGTGATCAACGGCTGCAATTTGTACAACGAC
AAAGAGATGAAGCACACCGTTTTGTCATTGCTTTTCATAAAAAACAAAAAAGAAAAGAGGACAAACAGATATCCCTTCTA
CAACTGCATGGCATCGGTGAAGCAAAAGTCAAAAAATTGCTTTTATATTTTGGTACTTTTGAAGAGATAAAACGTGCAAA
AGTTGAAACACTCAAAGAGGTTTTAAACGAAAAAGATGCTATTGTTTTATTTAACCATTTTACATCAAATAAAAATTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(14-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-543)

UvrB/uvrC motif (UVR)

(204-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.667

98.039

0.497

Multiple sequence alignment